Transoesophageal Echocardiography in Liver Transplantation
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ClinicalTrials.gov Identifier: NCT00547924 |
Recruitment Status
:
Completed
First Posted
: October 23, 2007
Last Update Posted
: April 10, 2014
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Severe hypotension during reperfusion in liver transplantation is a frequent adverse event. Rare data exist so far about pathophysiology of this phenomenon. The exact role of left ventricular function, which might be impaired causing hypotension, has not been elucidated during the period of reperfusion.
Goal of this study is to:
- perform transesophageal echocardiography in order to assess systolic and diastolic left ventricular function during reperfusion
- determine inflammatory mediators in the plasma which could cause left ventricular dysfunction
Condition or disease | Intervention/treatment |
---|---|
End Stage Liver Disease | Behavioral: Transoesophageal echocardiography |
Study Type : | Observational |
Estimated Enrollment : | 17 participants |
Observational Model: | Case-Only |
Time Perspective: | Prospective |
Official Title: | Transoesophageal Echocardiography in Liver Transplantation: Left Ventricular Function During Reperfusion |
Study Start Date : | April 2006 |
Actual Primary Completion Date : | January 2010 |
Actual Study Completion Date : | January 2010 |

-
Behavioral: Transoesophageal echocardiography

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Ages Eligible for Study: | 18 Years to 75 Years (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Probability Sample |
Inclusion criteria:
- Patients on waiting list for liver transplantation.
- Age: 18-75 years.
Exclusion criteria:
- Strictures, tumours and diverticula of the oesophagus.
- History of oesophageal varices with recent bleeding.
- Oesophageal varices and prothrombin time less than 20% or platetlets les than 30000/ml.
- Instable cervical spine.
- Involvement in other studies.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00547924
Switzerland | |
University Hospital Zurich, Institute for Anesthesiology | |
Zurich, Switzerland |
Principal Investigator: | Marco Zalunardo, MD | UniversitaetsSpital Zuerich |
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | University of Zurich |
ClinicalTrials.gov Identifier: | NCT00547924 History of Changes |
Other Study ID Numbers: |
StV 11-2006 |
First Posted: | October 23, 2007 Key Record Dates |
Last Update Posted: | April 10, 2014 |
Last Verified: | April 2014 |
Additional relevant MeSH terms:
Liver Diseases End Stage Liver Disease Digestive System Diseases Liver Failure Hepatic Insufficiency |