Relationship Between Microcirculatory Flow Alterations and Tissue Metabolism
The purpose of this study is to correlate microcirculatory flow and rectal anaerobe cellular CO2 production in patients after cardiac surgery. The hypothesis is that such a correlation exists.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Correlation Between Microcirculatory Flow and Rectal Anaerobe Cellular CO2 Production in Patients After Cardiac Surgery|
- Relation between MFI (by SDF) and capno [ Time Frame: 6 months ] [ Designated as safety issue: No ]
- Relevance of changes in flow and metabolism [ Time Frame: 6 months ] [ Designated as safety issue: No ]
|Study Start Date:||November 2007|
|Study Completion Date:||November 2008|
|Primary Completion Date:||October 2008 (Final data collection date for primary outcome measure)|
Sidestream Darkfield imaging is used to determine rectal microcirculatory flow in patients after postoperative cardiac surgery. At the same time PCO2 gap is established by monitoring rectal CO2 (tonometry) and arterial CO2 After initial enrollment and first analysis we also includes a control group with equal inclusion criteria for sublingual SDF imaging.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00547859
|Department of ICU|
|Leeuwarden, PO box 888, Netherlands, 8901BR|
|Principal Investigator:||E.C. Boerma, MD||Medical Centre Leeuwarden|