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Gas Usage for Those With COPD Who Experience Low Oxygen Levels During Activities Only

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ClinicalTrials.gov Identifier: NCT00546299
Recruitment Status : Completed
First Posted : October 18, 2007
Last Update Posted : October 18, 2007
Information provided by:

Study Description
Brief Summary:
Several studies have described the use of supplemental oxygen during exertion or activities of daily living (ambulatory oxygen) in study populations that have different characteristics. This report, based on specialized randomized controlled trials, characterizes ambulatory gas usage among patients with COPD who experience low oxygen levels during activities.

Condition or disease Intervention/treatment
Chronic Obstructive Pulmonary Disease Drug: oxygen

Study Design

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 27 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Ambulatory Gas Usage in Patients With COPD and Exertional Hypoxemia
Study Start Date : February 2003
Study Completion Date : December 2005

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Oxygen Therapy
U.S. FDA Resources

Arms and Interventions

Intervention Details:
    Drug: oxygen
    cylinder and concentrator, dosage to maintain SpO2 above 92%, used during exertion

Outcome Measures

Primary Outcome Measures :
  1. gas usage [ Time Frame: 2 ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Diagnosis of COPD
  • dyspnea limiting daily activities
  • desaturation less than or equal to 88% for 2 continuous minutes during a room air six-minute walk test

Exclusion Criteria:

  • less than or equal to 18 years old
  • those who met criteria for mortality reduction with long-term oxygen
  • those who received oxygen for palliative care or isolated nocturnal hypoxemia
  • those unable to complete the questionnaires or provide informed consent
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00546299

Sponsors and Collaborators
West Park Healthcare Centre
University of Toronto
Hamilton Health Sciences Corporation
Ontario Ministry of Health and Long Term Care
Study Director: Roger Goldstein, MD Respiratory Rehabilitation, West Park Healthcare Centre
More Information

ClinicalTrials.gov Identifier: NCT00546299     History of Changes
Other Study ID Numbers: 8-42361
First Posted: October 18, 2007    Key Record Dates
Last Update Posted: October 18, 2007
Last Verified: October 2007

Keywords provided by West Park Healthcare Centre:
Ambulatory oxygen therapy
exertional hypoxemia

Additional relevant MeSH terms:
Lung Diseases
Lung Diseases, Obstructive
Pulmonary Disease, Chronic Obstructive
Respiratory Tract Diseases