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The Effect Of Light On Scar Appearance

This study has been terminated.
(Study personnel left institution before study completion.)
Information provided by:
Northwestern University Identifier:
First received: October 12, 2007
Last updated: July 25, 2014
Last verified: July 2014
The goal of this project is to examine the ability of light exposure to improve the appearance of cutaneous scars.

Condition Intervention
Cutaneous Scars Device: no intervention Device: light

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: The Effect Of Light On Scar Appearance

Resource links provided by NLM:

Further study details as provided by Northwestern University:

Primary Outcome Measures:
  • Scar vascularity [ Time Frame: 24 weeks ]
  • Scar pigmentation [ Time Frame: 24 weeks ]
  • Scar thickness [ Time Frame: 24 weeks ]
  • Scar length [ Time Frame: 24 weeks ]
  • Scar width [ Time Frame: 24 weeks ]
  • Scar surface area [ Time Frame: 24 weeks ]

Estimated Enrollment: 50
Study Start Date: November 2005
Study Completion Date: August 2006
Primary Completion Date: August 2006 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: A
scars will be treated with light
Device: light
scars will be treated with light
Placebo Comparator: B
no intervention
Device: no intervention
no intervention

Detailed Description:
Light would be efficacious in improving scar appearance due to its known effects on wound healing, acne, and its use for skin rejuvenation. Light interacts with cells and stimulates the production of new collagen and elastin. This same energy can be used to inhibit collagen formation and help improve scars.

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Have two lesions that have been selected for excision
  • Have two cutaneous scars from previous excisions as part of a standard of care
  • Subjects are in good health
  • Subject has a willingness and the ability to understand and provide informed consent for the use of their tissue and communicate with the investigator

Exclusion Criteria:

  • Pregnancy or lactation
  • Subjects who are unable to understand the protocol or to give informed consent
  • Subjects with mental illness
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00544635

United States, Illinois
Northwestern Memorial Hospital
Chicago, Illinois, United States, 60611
Sponsors and Collaborators
Northwestern University
Principal Investigator: Murad Alam, MD Northwestern University
  More Information

Responsible Party: Murad Alam, MD, Northwestern University Identifier: NCT00544635     History of Changes
Other Study ID Numbers: 1253-010
Study First Received: October 12, 2007
Last Updated: July 25, 2014 processed this record on August 22, 2017