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This is a clinical trial in patients with Type 2 Diabetes to test the safety of MK0767. This study will also see how effective MK0767 is in lowering markers of glucose metabolism and improving the lipid profile and non-HDL cholesterol when compared with placebo and pioglitazone.
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Layout table for eligibility information
Ages Eligible for Study:
21 Years to 75 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Type 2 Diabetes Mellitus patients between the ages of 21 and 75 inclusive
Patient is willing to discontinue current therapy for the duration of the study
Patient is not a heavy drinker
Patient has a history of Type 1 diabetes and/or ketoacidosis
Patient has severe diabetic retinopathy, or nephropathy, or neuropath
Patient has has anti-hyperglycemic therapy including insulin, or rosiglitazone and pioglitazone or 2 or more oral agents in combination within 8 weeks prior to visit 1
Patient has a history of, allergy to, intolerance or hypersensitive to troglitazone, rosiglitazone, or pioglitazone including history of elevated liver function test, jaundice, or hepatotoxicity associated with these treatments