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MK0767 in Type 2 Diabetes (0767-012)

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ClinicalTrials.gov Identifier: NCT00543556
Recruitment Status : Terminated
First Posted : October 15, 2007
Last Update Posted : June 15, 2015
Sponsor:
Information provided by (Responsible Party):
Merck Sharp & Dohme Corp.

Brief Summary:
This is a clinical trial in patients with Type 2 Diabetes to test the safety of MK0767. This study will also see how effective MK0767 is in lowering markers of glucose metabolism and improving the lipid profile and non-HDL cholesterol when compared with placebo and pioglitazone.

Condition or disease Intervention/treatment Phase
Type 2 Diabetes Mellitus Drug: MK0767 Phase 2

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 514 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Treatment
Study Start Date : October 2001
Actual Primary Completion Date : November 2003
Actual Study Completion Date : November 2003

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U.S. FDA Resources





Information from the National Library of Medicine

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Ages Eligible for Study:   21 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Type 2 Diabetes Mellitus patients between the ages of 21 and 75 inclusive
  • Patient is willing to discontinue current therapy for the duration of the study
  • Patient is not a heavy drinker

Exclusion Criteria:

  • Patient has a history of Type 1 diabetes and/or ketoacidosis
  • Patient has severe diabetic retinopathy, or nephropathy, or neuropath
  • Patient has has anti-hyperglycemic therapy including insulin, or rosiglitazone and pioglitazone or 2 or more oral agents in combination within 8 weeks prior to visit 1
  • Patient has a history of, allergy to, intolerance or hypersensitive to troglitazone, rosiglitazone, or pioglitazone including history of elevated liver function test, jaundice, or hepatotoxicity associated with these treatments

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00543556


Sponsors and Collaborators
Merck Sharp & Dohme Corp.
Investigators
Study Director: Medical Monitor Merck Sharp & Dohme Corp.

Responsible Party: Merck Sharp & Dohme Corp.
ClinicalTrials.gov Identifier: NCT00543556     History of Changes
Other Study ID Numbers: 0767-012
2007_640
First Posted: October 15, 2007    Key Record Dates
Last Update Posted: June 15, 2015
Last Verified: June 2015

Additional relevant MeSH terms:
Diabetes Mellitus
Diabetes Mellitus, Type 2
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases