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Establishment of an Algorithm for a Clinical Classfication of Hypoosmolar Hyponatremia (CONA)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00541944
Recruitment Status : Unknown
Verified April 2008 by University of Wuerzburg.
Recruitment status was:  Recruiting
First Posted : October 10, 2007
Last Update Posted : April 28, 2008
Information provided by:
University of Wuerzburg

Brief Summary:
The prospective clinical diagnosis of hyponatremia is often very difficult- but requirement for an appropriate and riskless treatment of hyponatremia. This study try to establish an algorithm handling a prospective clinical categorization of hyponatremia and approving together the start of an appropriate symptomatic therapy.

Condition or disease

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Study Type : Observational
Estimated Enrollment : 120 participants
Observational Model: Cohort
Time Perspective: Prospective
Study Start Date : April 2007
Estimated Study Completion Date : December 2008

Primary Outcome Measures :
  1. Establishment of an clinical algorithm to differentiate the different causes of hyponatremia [ Time Frame: One year ]

Biospecimen Retention:   Samples Without DNA
Serum, plasma and urine

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Patients treated in an University Hospital in Germany

Inclusion Criteria:

  • hypoosmolar hyponatremia with serum sodium concentration ≤129 mmol/l and serum osmolality ≤ 280 mosm/kg;
  • age > 18 years;
  • letter of agreement.

Exclusion Criteria:

  • gravidity and lactation;
  • restricted decision-making-ability

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00541944

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Contact: Bruno Allolio, MD 49-931-201-36109
Contact: Wiebke Fenske, MD 49-931-201-36774

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University of Wuerzburg Recruiting
Wuerzburg, Germany, 97080
Contact: Bruno Allolio, MD         
Contact: Wiebke Fenske, MD         
Sponsors and Collaborators
University of Wuerzburg
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Principal Investigator: Bruno Allolio, MD Universtiy of Wuerzburg
Publications automatically indexed to this study by Identifier (NCT Number):
Layout table for additonal information Identifier: NCT00541944    
Other Study ID Numbers: Wue-CONA-33/07
First Posted: October 10, 2007    Key Record Dates
Last Update Posted: April 28, 2008
Last Verified: April 2008
Keywords provided by University of Wuerzburg:
diagnosis and treatment of hyponatremia
classification of hyponatremia
Additional relevant MeSH terms:
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Water-Electrolyte Imbalance
Metabolic Diseases