Combined CT Colonography and PET Imaging in Mantle Cell Lymphoma
The goal of this clinical research study is to learn if positron emission tomography (PET)/computed tomography (CT) scanning can be used to detect mantle cell lymphoma in the colon. Researchers want to learn if PET/CT scanning can produce good-quality images and/or find the exact locations of lymphoma in the body.
Primary Objective is to determine if combined CT colonography and full body PET scan is technically feasible and can produce diagnostic scans as well as accurate anatomic coordination for detection of mantle cell lymphoma involvement of the colon.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Feasibility of Combined CT Colonography and PET Imaging for Detection of Colonic Involvement by Mantle Cell Lymphoma|
- Number of Participants with PET/CT Scan Detection of Mantle Cell Lymphoma [ Time Frame: 1 Day, Participation completed day of CT colonography and full body PET scan ] [ Designated as safety issue: No ]
- Number of PET/CT Scanning Images Locating Exact Lymphoma Locations [ Time Frame: 2 years ] [ Designated as safety issue: No ]
|Study Start Date:||September 2007|
|Study Completion Date:||November 2008|
|Primary Completion Date:||November 2008 (Final data collection date for primary outcome measure)|
Patients that have newly diagnosed mantle cell lymphoma will first undergo CT colonography (CT or CTC) and PET followed by conventional colonoscopy.
Procedure: PET/CT Scanning
Full-body PET/CT procedure will be performed. Gas will be pumped into the colon before the scan so the colon will be opened up (inflated) and the study doctor will be able to more easily look for any lesions. This procedure is called gas insufflation.
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00541424
|Principal Investigator:||Revathy B. Iyer, MD||M.D. Anderson Cancer Center|