We are updating the design of this site. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Optical Biopsy of Human Skin in Conjunction With Laser Treatment

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00540566
First Posted: October 8, 2007
Last Update Posted: February 10, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
Beckman Laser Institute University of California Irvine
Information provided by (Responsible Party):
Beckman Laser Institute and Medical Center, University of California, Irvine
  Purpose
This study is to compare the ability of optical biopsy. Research can use light enters the skin, collected, analyzed by the computer, and a picture created for the pathologist to conventional histologic examination compare with the pathologist looking at the piece of tissue through a microscope makes the diagnosis.

Condition Intervention
Malignant Melanoma Merkel Cell Carcinoma Basal Cell Carcinoma Squamous Cell Carcinoma Atypical Nevi Congenital Nevi Seborrheic Keratosis Paget's Disease Dermatofibroma Kaposi's Sarcoma Port Wine Stain Hemangioma Tattoos Scleroderma Burns Device: Optical Biopsy imaging

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Optical Biopsy of Human Skin in Conjunction With Laser Treatment

Resource links provided by NLM:


Further study details as provided by Beckman Laser Institute and Medical Center, University of California, Irvine:

Primary Outcome Measures:
  • normal skin [ Time Frame: 12 weeks ]

Enrollment: 113
Study Start Date: June 1999
Study Completion Date: July 2008
Primary Completion Date: June 2008 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Optical Biopsy
Optical Biopsy imaging
Device: Optical Biopsy imaging
Optical Biopsy imaging

Detailed Description:
The Optical measurements provide quantitative optical property values that reflect changes in tissue perfusion, oxygen consumption, and cell/matrix development. Each measurement requires less than 5 minutes to execute. The measurements will be taken before and after skin treatment.This non-invasive, non-contact technique has great potential as a means to diagnose different skin problems without the need to obtain a piece of tissue from the skin.
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
primary care clinic, community sample
Criteria

Inclusion Criteria:

  • Male or female age > 18 years

Exclusion Criteria:

  • current participation in any other investigational drug evaluation
  • inability to understand and carry out instructions
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00540566


Locations
United States, California
Beckman Laser Institute, Unversity of California Irvine
Irvine, California, United States, 92612
Sponsors and Collaborators
University of California, Irvine
Beckman Laser Institute University of California Irvine
Investigators
Principal Investigator: John S Nelson, M.D,Ph.D Beckman Laser Institue, University of California Irvine
  More Information

Responsible Party: Beckman Laser Institute and Medical Center, J.S.Nelson, MD,PhD,Professor of Surgery and Biomedical Engineering, University of California, Irvine
ClinicalTrials.gov Identifier: NCT00540566     History of Changes
Other Study ID Numbers: NIH-LAMPP-1996-200
First Submitted: October 4, 2007
First Posted: October 8, 2007
Last Update Posted: February 10, 2017
Last Verified: February 2017

Additional relevant MeSH terms:
Histiocytoma, Benign Fibrous
Histiocytoma
Carcinoma
Carcinoma, Squamous Cell
Keratosis
Carcinoma, Basal Cell
Melanoma
Sarcoma, Kaposi
Hemangioma
Nevus
Carcinoma, Merkel Cell
Port-Wine Stain
Hemangioma, Capillary
Keratosis, Seborrheic
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Neoplasms
Neoplasms, Squamous Cell
Skin Diseases
Neoplasms, Basal Cell
Neuroendocrine Tumors
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms, Nerve Tissue
Nevi and Melanomas
Herpesviridae Infections
DNA Virus Infections
Virus Diseases
Sarcoma
Neoplasms, Connective and Soft Tissue