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Outcome and Related Factors of Necrotizing Fasciitis of the Limb

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00538577
Recruitment Status : Completed
First Posted : October 2, 2007
Last Update Posted : October 6, 2009
Information provided by:
Tehran University of Medical Sciences

Brief Summary:
Soft tissue necrotizing fasciitis of limbs are lethal infections and associated with high morbidity and mortality rates. The purpose of this study is to determine the clinical manifestations and factors affected the treatment outcome to predict the prognosis and make timely decision for appropriate management and prevent limb loss.

Condition or disease
Necrotizing Fasciitis

Detailed Description:
Patients that are admitted to hospital with the diagnosis of necrotizing fasciitis of a limb will be entered to this study. A questionnaire will be completed for each patient included demographic data, admission and diagnosis date, treatment onset, medical history for diabetes mellitus, HIV infection, use of immunosuppressor drugs, peripheral vascular disease, cancer, renal disease, intravenous drug abuse, and disease outcome that can be recovery, amputation or death.

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Study Type : Observational
Estimated Enrollment : 25 participants
Observational Model: Case Control
Time Perspective: Prospective
Study Start Date : September 2007
Actual Primary Completion Date : June 2009
Actual Study Completion Date : September 2009

Resource links provided by the National Library of Medicine

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
The Patients with diagnosis of necrotiying faciitis

Inclusion Criteria:

  • Necrotizing fasciitis of the limb

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00538577

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Iran, Islamic Republic of
Operative Theater of Orthopedic Surgery Department- Imam Khomeini Hospital
Tehran, Iran, Islamic Republic of
Sponsors and Collaborators
Tehran University of Medical Sciences
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Principal Investigator: Ramin Espandar, MD Imam Khomeini Hospital- Tehran University of Medical Sciences
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Responsible Party: Chacellor of Research, Tehran University of Medical Sciences Identifier: NCT00538577    
Other Study ID Numbers: 86-03-30-6110
First Posted: October 2, 2007    Key Record Dates
Last Update Posted: October 6, 2009
Last Verified: October 2009
Keywords provided by Tehran University of Medical Sciences:
Necrotizing fasciitis
Additional relevant MeSH terms:
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Fasciitis, Necrotizing
Musculoskeletal Diseases
Skin Diseases, Bacterial
Bacterial Infections