First Study of the Safety of CNTO 888 in Patients With Solid Tumors
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|ClinicalTrials.gov Identifier: NCT00537368|
Recruitment Status : Completed
First Posted : October 1, 2007
Last Update Posted : October 22, 2010
|Condition or disease||Intervention/treatment||Phase|
|Cancer||Drug: CNTO 888||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||44 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||A Phase 1 Study of CNTO 888, a Human Monoclonal Antibody Against CC-Chemokine Ligand 2 in Subjects With Solid Tumors|
|Study Start Date :||September 2007|
|Actual Study Completion Date :||March 2010|
- Evaluate the safety and pharmacokinetics (rate of movement in the body and then the clearance) of CNTO 888 administered as multiple intravenous (IV) infusions in patients with solid tumors throughout the course of the study.
- Assess the pharmacodynamics (action of drug on body systems), immune response and clinical effects (tumor response and time to disease progression) of CNTO888 when administered as multiple IV infusions in patients with solid tumors throughout the study.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00537368
|Study Director:||Centocor, Inc. Clinical Trial||Centocor, Inc.|