ClinicalTrials.gov
ClinicalTrials.gov Menu

MicroRNA Expression and Function in Cutaneous Malignant Melanoma

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00536029
Recruitment Status : Completed
First Posted : September 27, 2007
Last Update Posted : September 27, 2007
Sponsor:
Information provided by:
Rigshospitalet, Denmark

Brief Summary:
Spectrophotometric intracutaneous analysis (SIAscopy) is a new technique for imaging pigmented skin lesions and for diagnosing melanoma and non-melanoma skin cancer. The SIAscope is a portable system comprising of a laptop computer connected to a small handheld skin probe equipped with a light source. The skin lesion is interrogated with light of different wavelengths and the reflection spectra analysed by proprietary algorithms showing distribution, position and quantity of melanin, blood and collagen within the papillary dermis (the SIAgraphs). Earlier studies generated promising results and documented >80% specificity and sensitivity of SIAscopy for melanoma diagnosis. It has been suggested that this technique could be used for the initial screening and selection of pigmented lesion for excision. In this work we addressed the usefulness of SIAscopy for the clinical diagnosis of pigmented malignant melanoma in a prospective, blinded design.

Condition or disease
Melanoma

Study Type : Observational
Actual Enrollment : 68 participants
Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: MicroRNA Expression and Function in Cutaneous Malignant Melanoma
Study Start Date : February 2007
Actual Study Completion Date : June 2007

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Melanoma
U.S. FDA Resources

Group/Cohort
Case: A
Subject with pigmented skin lesion suspect for malignant melanoma




Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Pigmented lesion

Exclusion Criteria:

  • No pigmented lesion

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00536029


Locations
Denmark
Rigshospitalet
Copenhagen, Denmark, 2200
Sponsors and Collaborators
Rigshospitalet, Denmark
Investigators
Principal Investigator: Martin Glud, Cand.med. Department for Plastic Surgery and Burn Unit

Publications:
ClinicalTrials.gov Identifier: NCT00536029     History of Changes
Other Study ID Numbers: H-C-2007-0009
First Posted: September 27, 2007    Key Record Dates
Last Update Posted: September 27, 2007
Last Verified: September 2007

Keywords provided by Rigshospitalet, Denmark:
Melanoma
SIAscope
pigmented skin lesions

Additional relevant MeSH terms:
Melanoma
Neuroendocrine Tumors
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms
Neoplasms, Nerve Tissue
Nevi and Melanomas