Duodenal Exclusion for the Treatment of Type 2 Diabetes
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The purpose of this study is to investigate the role of an experimental surgery that may offer better short and long-term control of T2DM in select patients who have not achieved adequate blood sugar control with regular means.
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Ages Eligible for Study:
20 Years to 50 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Age between 20 and 50 years old;
BMI between 27 and 34.9;
Oral agents or insulin to control T2DM;
Inadequate control of diabetes as defined as HbA1c>8.0% but <10%
Understanding of the mechanisms of action of the treatment
More than 5 years of T2DM diagnosis;
C-peptide <1pg/ml (off insulin)
Previous abdominal operations;
History of gastritis
History of GERD
History of peptic ulcer disease
Inflammatory bowel disease
Unable to comply with study requirements, follow-up schedule or give valid informed consent;
Currently pregnant (pregnancy test required for confirmation for those of child bearing years)
Patient is not available for programmed follow-up during the study period
Patient is unwilling to forgo good samaritan blood donation during the study period