The ROVO Study: Radial Optic Neurotomy for CVO
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|ClinicalTrials.gov Identifier: NCT00532142|
Recruitment Status : Completed
First Posted : September 20, 2007
Last Update Posted : October 30, 2009
The ROVO study is a prospective, placebocontrolled and randomised study designed to evaluate the effect of radial optic neurotomy in central vein occlusion, versus triamcinolone acetonide. 240 patients with a visual acuity < 0.5 Snellen will be randomised. Patients are treated with either RON, or a single intravitreal injection of 4 mg triamcinolone acetonide, or a placebo treatment - a "sham" injection of intravitreal triamcinolone. Patients will be examined regularly over a period of one year.
Best corrected visual acuity for far and near, as well as clinical examinations, fluorescein- and indocyanine green angiograms, optical coherence tomography, and perimetry, are performed pre- and postoperatively.
|Condition or disease||Intervention/treatment||Phase|
|Central Retinal Vein Occlusion||Drug: Intravitreal Triamcinolone Procedure: Radial Optic Neurotomy Other: Placebo - Sham Intravitreal Injection||Phase 2 Phase 3|
|Study Type :||Interventional (Clinical Trial)|
|Intervention Model:||Parallel Assignment|
|Official Title:||A Multicenter Trial for Surgical Treatment of Central Retinal Vein Occlusion - Radial Optic Neurotomy for CVO The ROVO Study|
|Study Start Date :||April 2005|
|Actual Study Completion Date :||August 2009|
- Proportion of eyes with an improvement of more than 15 letters (approximately > 3 lines of visual acuity gain) after one year as compared to baseline
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00532142
|Rudolf foundation Clinic|
|Vienna, Austria, A1030|
|Study Chair:||Susanne Binder, M.D.||no affiliation|