The ROVO Study: Radial Optic Neurotomy for CVO
The ROVO study is a prospective, placebocontrolled and randomised study designed to evaluate the effect of radial optic neurotomy in central vein occlusion, versus triamcinolone acetonide. 240 patients with a visual acuity < 0.5 Snellen will be randomised. Patients are treated with either RON, or a single intravitreal injection of 4 mg triamcinolone acetonide, or a placebo treatment - a "sham" injection of intravitreal triamcinolone. Patients will be examined regularly over a period of one year.
Best corrected visual acuity for far and near, as well as clinical examinations, fluorescein- and indocyanine green angiograms, optical coherence tomography, and perimetry, are performed pre- and postoperatively.
|Central Retinal Vein Occlusion||Drug: Intravitreal Triamcinolone Procedure: Radial Optic Neurotomy Other: Placebo - Sham Intravitreal Injection||Phase 2 Phase 3|
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Participant)
Primary Purpose: Treatment
|Official Title:||A Multicenter Trial for Surgical Treatment of Central Retinal Vein Occlusion - Radial Optic Neurotomy for CVO The ROVO Study|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00532142
|Rudolf foundation Clinic|
|Vienna, Austria, A1030|
|Study Chair:||Susanne Binder, M.D.||no affiliation|