Evaluation of the Emission Distance of P. Aeruginosa From the Respiratory Tract of People With Cystic Fibrosis
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|ClinicalTrials.gov Identifier: NCT00531531|
Recruitment Status : Completed
First Posted : September 19, 2007
Last Update Posted : August 23, 2011
It is well known that an association exists between the acquisition of some respiratory pathogens and prognosis of CF people. About 57 % of patients has a lung infection due to P.aeruginosa (PA). Transmission of PA between CF patients is possible and several prevention measures are recommended. Among these measures, all international guidelines recommend that CF people maintain a minimum distance of 1 meter between them. However, this recommendation is not supported by specific studies and scientific evidence. In other words, the investigators don't know if this measure is sufficient or excessive, as it is based only on a theoretical rationale.
This study aims at measuring experimentally the distance that can be reached by PA emitted from airways of colonized CF patients during cough and during conversation.
To this purpose, the investigators will evacuate the presence of PA on surfaces placed at 4 different distances from patients, through the collection of 8 swabs, 4 of which following cough and 4 following conversation. Swabs will be collected on sterile surfaces comprised between tra 0 - 0,5 mt; 0,5 -1,00 mt.; 1,00 - 1,5 mt and 1.5-2 mt.
All the PA-positive CF patients of the CF Centre of Tuscany aged 14 or more will be recruited.
|Condition or disease|
Show Detailed Description
|Study Type :||Observational|
|Actual Enrollment :||42 participants|
|Official Title:||Control and Prevention of Respiratory Infections in Cystic Fibrosis Patients: an Evaluation of the Emission Distance of P. Aeruginosa From the Respiratory Tract of Infected Persons Through Coughing and Conversation.|
|Study Start Date :||September 2007|
|Primary Completion Date :||August 2008|
|Study Completion Date :||August 2008|
- Prevalence of surface samples positive for PA [ Time Frame: six months ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00531531
|Cystic Fibrosis Center of Tuscany, Meyer Hospital|
|Florence, Italy, 50132|
|Study Chair:||Filippo Festini, BN, BSN, RN||University of Florence, Italy|
|Study Director:||Cesare Braggion, MD||Cystic Fibrosis Center, Meyer Hospital Florence|