Postoperative Analgesia With Local Infiltration After Femoral Neck Fracture

This study has been completed.
Information provided by:
Odense University Hospital Identifier:
First received: September 12, 2007
Last updated: May 5, 2010
Last verified: April 2010
Reducing pain is an essential factor for early mobilization after osteosynthesis of femoral neck fractures. Systemic opioids have side effects that might obstruct mobilization and induce delirium and nausea. The investigators hypothesized that wound infiltration results in reduction in systemic opioid usage and pain relief without side effects.

Condition Intervention Phase
Femoral Neck Fracture
Drug: Ropivacaine
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Postoperative Analgesia With Local Infiltration After Femoral Neck Fracture vs. Traditional Treatment of Pain With Opioids

Resource links provided by NLM:

Further study details as provided by Odense University Hospital:

Primary Outcome Measures:
  • Consumption of opioids

Secondary Outcome Measures:
  • Pain

Enrollment: 50
Study Start Date: January 2008
Study Completion Date: December 2008
Arms Assigned Interventions
Active Comparator: Ropivacaine Drug: Ropivacaine
Placebo Comparator: Saline Drug: Ropivacaine


Genders Eligible for Study:   Both

Inclusion Criteria:

  • Femoral neck fracture
  • Fracture due to low energy trauma
  • Ability to understand danish and give informed consent
  • Ability to walk before trauma
  • Indication for osteosynthesis
  • ≥ 8 in OMC (Orientation-Memory-Concentration) test with a possible maximum of 28 points
  • Informed consent

Exclusion Criteria:

  • Drug or medical abuse
  • Drug intolerance
  • Pathological fractures
  • Inflammatory arthritis
  • Patient included in the study with the contralateral hip
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Please refer to this study by its identifier: NCT00529425

Odense University Hospital
Odense, Denmark, 5000
Sponsors and Collaborators
Odense University Hospital
Study Chair: Soren Overgaard, Professor, MD, DmSc Odense University Hospital, DK-5000 Odense C, Denmark
Principal Investigator: Rune Dueholm Bech, MD Odense University Hospital, DK-5000 Odense C, Denmark
  More Information

No publications provided by Odense University Hospital

Additional publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00529425     History of Changes
Other Study ID Numbers: S-VF-20060072 - femoral neck
Study First Received: September 12, 2007
Last Updated: May 5, 2010
Health Authority: Denmark: Danish Medicines Agency

Keywords provided by Odense University Hospital:
Femoral neck fracture
Hip fracture

Additional relevant MeSH terms:
Femoral Neck Fractures
Fractures, Bone
Femoral Fractures
Hip Fractures
Leg Injuries
Wounds and Injuries
Anesthetics, Local
Central Nervous System Agents
Central Nervous System Depressants
Peripheral Nervous System Agents
Pharmacologic Actions
Physiological Effects of Drugs
Sensory System Agents
Therapeutic Uses processed this record on November 27, 2015