Plasma B-Type Natriuretic Peptide Concentrations in Preterm Infants < 28 Weeks
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|ClinicalTrials.gov Identifier: NCT00528736|
Recruitment Status : Completed
First Posted : September 12, 2007
Last Update Posted : September 14, 2007
|Condition or disease|
|Infant, Premature Ductus Arteriosus, Patent Natriuretic Peptide Brain|
From the study infants blood samples (0.1ml) were collected in K-EDTA microtubes within 24 to 48 hours of age through umbilical artery catheter aspiration or routine venous puncture. The samples were spun at 7000 rpm for 3 minutes. Platelet-free plasma was stored at -20°C until BNP analysis of all collected samples was carried out. The BNP assay was performed using a fully automated immunoassay system ADVIA method for the Centaur System (Bayer Diagnostic Division).
In preterm infants who were treated with indomethacin or surgical ligation we collected additional blood samples 2-4 hours before intervention and 24 hours after the completion of the ductus treatment.
|Study Type :||Observational|
|Actual Enrollment :||82 participants|
|Observational Model:||Defined Population|
|Study Start Date :||August 2005|
|Actual Study Completion Date :||April 2007|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00528736
|Department of Neonatology, Charite Virchow Hospital, Medical University Berlin|
|Berlin, Germany, 13353|
|Study Director:||Christoph Czernik, MD||Department of Neonatology, Charite Virchow Hospital, Medical University Berlin|