Try our beta test site
IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...

Treatment of M.Graves With Radioactive Iodine: Follow-up Study

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified May 2008 by Medisch Centrum Rijnmond-Zuid, Netherlands.
Recruitment status was:  Recruiting
Information provided by:
Medisch Centrum Rijnmond-Zuid, Netherlands Identifier:
First received: September 4, 2007
Last updated: May 21, 2008
Last verified: May 2008

Hypothesis: What is the natural course after treatment with radioactive iodine in patients with hyperthyroidism?

What are the determinants for the development of acute hypo- or hyperthyroidism after treatment with radioactive iodine without antithyroid drugs?


Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by Medisch Centrum Rijnmond-Zuid, Netherlands:

Estimated Enrollment: 100
Study Start Date: September 2007
Patients with hyperthyroidism who are will be treated with radioactive iodine.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients of 18 years and older with hyperthyroidism who are eligible for treatment with radioactive iodine.

Inclusion Criteria:

  • Patients wth hyperthyroidism who are eligible for treatment with radioactive iodine
  • Age > 18 years

Exclusion Criteria:

  • Severe ophthalmopathy
  • Pregnancy or wish to pregnancy on short term
  • Breastfeeding
  • Patients already treated with radioactive iodine
  • Known cardiovascular diseases or other severe comorbidity
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00525122

Contact: A. Berghout, MD, PhD 0031 10 2913368

MCRZ Recruiting
Rotterdam, Zuid-Holland, Netherlands, 3075 EA
Contact: A Berghout, MD, PhD         
Sponsors and Collaborators
Medisch Centrum Rijnmond-Zuid, Netherlands
Principal Investigator: A. Berghout, MD, PhD Medisch Centrum Rijnmond-Zuid, Netherlands
Principal Investigator: C. van Noord, MD Medisch Centrum Rijnmond-Zuid, Netherlands
  More Information

Responsible Party: A. Berghout, MCRZ Identifier: NCT00525122     History of Changes
Other Study ID Numbers: 2006/60
Study First Received: September 4, 2007
Last Updated: May 21, 2008

Keywords provided by Medisch Centrum Rijnmond-Zuid, Netherlands:
radioactive iodine
antithyroid drugs
Hyperthyroidism, treatment with radioactive iodine without antithyroid drugs

Additional relevant MeSH terms:
Thyroid Diseases
Endocrine System Diseases
Antithyroid Agents
Hormone Antagonists
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs
Anti-Infective Agents, Local
Anti-Infective Agents
Trace Elements
Growth Substances processed this record on May 25, 2017