How to Improve Diagnosis in Infective Endocarditis
|ClinicalTrials.gov Identifier: NCT00524212|
Recruitment Status : Completed
First Posted : September 3, 2007
Last Update Posted : January 20, 2010
|Condition or disease|
Despite progress in surgical and medical treatment, infective endocarditis is still associated with high morbidity and mortality.
The variable clinical presentation of IE makes the diagnosis a clinical challenge.
Procalcitonin is a precursor from the hormone calcitonin and also a marker of systemic bacterial infections.
The purpose of this study is:
- to investigate the diagnostic value of serum procalcitonin (PCT), C-reactive protein (CRP) and sedimentation rate (SR) when IE is suspected.
- to investigate if a retrospectively generated clinical model suitable for exclusion of IE can be confirmed prospectively.
|Study Type :||Observational|
|Actual Enrollment :||761 participants|
|Official Title:||Ph. D Student, Jane Byriel Knudsen, Aarhus University|
|Study Start Date :||March 2007|
|Actual Study Completion Date :||May 2009|
IE confirmed IE rejected
Prospective, controlled, blinded study of clinical/TEE criteria of IE compare to clinical/blood test criteria of IE.
|IE confirmed IE rejected|
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00524212
|Department of Cardiology, Aarhus University Hospital|
|Aarhus, Denmark, 8200|
|Principal Investigator:||Jane B Knudsen, Dr.||Aarhus University Hospital, Skejby, Department of Cardiology, 8200 Aarhus N, Denmark|