How to Improve Diagnosis in Infective Endocarditis
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00524212|
Recruitment Status : Completed
First Posted : September 3, 2007
Last Update Posted : January 20, 2010
|Condition or disease|
Despite progress in surgical and medical treatment, infective endocarditis is still associated with high morbidity and mortality.
The variable clinical presentation of IE makes the diagnosis a clinical challenge.
Procalcitonin is a precursor from the hormone calcitonin and also a marker of systemic bacterial infections.
The purpose of this study is:
- to investigate the diagnostic value of serum procalcitonin (PCT), C-reactive protein (CRP) and sedimentation rate (SR) when IE is suspected.
- to investigate if a retrospectively generated clinical model suitable for exclusion of IE can be confirmed prospectively.
|Study Type :||Observational|
|Actual Enrollment :||761 participants|
|Official Title:||Ph. D Student, Jane Byriel Knudsen, Aarhus University|
|Study Start Date :||March 2007|
|Actual Study Completion Date :||May 2009|
IE confirmed IE rejected
Prospective, controlled, blinded study of clinical/TEE criteria of IE compare to clinical/blood test criteria of IE.
|IE confirmed IE rejected|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00524212
|Department of Cardiology, Aarhus University Hospital|
|Aarhus, Denmark, 8200|
|Principal Investigator:||Jane B Knudsen, Dr.||Aarhus University Hospital, Skejby, Department of Cardiology, 8200 Aarhus N, Denmark|