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Diagnosis and Characterization of Coronary Artery Stenosis by Doppler Ultrasound

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified March 2007 by Hillel Yaffe Medical Center.
Recruitment status was:  Not yet recruiting
Information provided by:
Hillel Yaffe Medical Center Identifier:
First received: August 24, 2007
Last updated: NA
Last verified: March 2007
History: No changes posted
The purpose of this study is to evaluate the feasibility of acquisition of coronary blood flow velocity signals over the whole length of the LAD with transthoracic pulsed Doppler, and to evaluate the diagnostic power of the transthoracic Doppler analysis package for detecting and estimating the degree of coronary artery stenosis. Finally we hope to optimize the currently available analysis package on the basis of the comparison of the Doppler with the angiographic stenosis results and evaluation.

Coronary Stenosis

Study Type: Observational
Study Design: Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Prospective
Official Title: Diagnosis and Characterization of Coronary Artery Stenosis by Transthoracic Doppler Ultrasound

Further study details as provided by Hillel Yaffe Medical Center:

Study Start Date: August 2007
Case: A
Patients with an acute coronary syndrome that are candidates for coronary angiography. Doppler results will be compared to angiographic findings.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All

Inclusion Criteria:

  • Patients who are clinically suspected of having significant coronary artery stenosis.
  • Patients with CAD.
  • Patients who are scheduled to undergo coronary angiography.
  • Signed informed consent.

Exclusion Criteria:

  • Patients with arrhythmia / irregular pulse
  • Patients with unstable conditions: unstable angina, uncontrolled CHF
  • Patients with COPD
  • Any physical or medical disability that prevent lying in supine position
  • Patients with chest wall deformity
  Contacts and Locations
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Please refer to this study by its identifier: NCT00521326

Contact: Simcha R Meisel, MD, MSc 972-4-630-4656
Contact: Avraham Shotan, MD 972-4-630-4428

Coronary Care Unit, Heart Institute, Hille Yaffe Medical Center Not yet recruiting
Hadera, Israel, 38100
Contact: Simcha R Meisel, MD, MSc    972-4-630-4656   
Principal Investigator: Simcha R Meisel, MD, MSc         
Sponsors and Collaborators
Hillel Yaffe Medical Center
Principal Investigator: Simcha R Meisel, MD, MSc Hillel Yaffe Medical Center
  More Information Identifier: NCT00521326     History of Changes
Other Study ID Numbers: DOP01
Study First Received: August 24, 2007
Last Updated: August 24, 2007

Keywords provided by Hillel Yaffe Medical Center:
coronary stenosis
non-invasive testing
A prospective study of a new diagnostic method.
Study consists of a transthoracic doppler of LAD.
Doppler to be performed prior to coronary angiography.
F/U doppler examination for those who undergo PCI.
Doppler results will be compared with coronary angiography.

Additional relevant MeSH terms:
Constriction, Pathologic
Coronary Stenosis
Pathological Conditions, Anatomical
Coronary Disease
Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Vascular Diseases processed this record on May 24, 2017