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T2* in Transfusion Dependant Anemia, MI, LVF, Normal Patients

This study has been completed.
Information provided by:
Imperial College London Identifier:
First received: August 23, 2007
Last updated: NA
Last verified: August 2007
History: No changes posted
The purpose of this study is to provide accurate prognostic data linking cardiac complications to myocardial T2* values (A measure of iron levels in the heart using MRI)in patients predisposed to heart iron overload.


Study Type: Observational
Study Design: Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Retrospective
Official Title: Incidence of Cardiac Complications in Patients With Cardiac Siderosis During 1 Year Follow−up and the Normal T2* Ranges in LVF, MI and Normal Population.

Resource links provided by NLM:

Further study details as provided by Imperial College London:

Enrollment: 665
Study Start Date: January 2007
Study Completion Date: August 2007
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Ages Eligible for Study:   Child, Adult, Senior
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Thalassaemia Major
  • Patient must have had a cardiac MRI scan between 1999 and 2006

Exclusion Criteria:

  • Other structural heart disease such as valvular abnormalities, MI, congenital heart disease
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00520559

Sponsors and Collaborators
Imperial College London
Principal Investigator: Dudley Pennell, MA, MD Imperial College London
  More Information

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00520559     History of Changes
Other Study ID Numbers: 07/MRE04/32 
Study First Received: August 23, 2007
Last Updated: August 23, 2007
Health Authority: United Kingdom: National Health Service
United Kingdom: Research Ethics Committee

Additional relevant MeSH terms:
Anemia, Hemolytic, Congenital
Anemia, Hemolytic
Hematologic Diseases
Genetic Diseases, Inborn processed this record on October 21, 2016