Celecoxib for Reducing Morphine Requirement After Thyroid Surgery: A Randomized Controlled Trial
|ClinicalTrials.gov Identifier: NCT00520338|
Recruitment Status : Completed
First Posted : August 24, 2007
Last Update Posted : November 9, 2010
The purpose of this study is to determine whether celecoxib is effective in the treatment postoperative pain after thyroidectomy.
The research hypothesis:
There is a difference in postoperative morphine consumption in the first 24 hours after thyroidectomy between patients who received celecoxib or placebo.
|Condition or disease||Intervention/treatment||Phase|
|Postoperative Pain Thyroidectomy Cyclooxygenase 2 Inhibitors||Drug: celecoxib||Phase 4|
Postoperative pain has been concerned in the past few years by both the anesthesiologists ans the surgeons. COX2-inhibitors have played an important roles in postoperative pain with minimal side effects.
Comparison(s): There is a difference in postoperative morphine consumption in the first 24 hours after thyroidectomy between patients who received celecoxib and placebo.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||80 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)|
|Official Title:||Celecoxib for Reducing Morphine Requirement After Thyroid Surgery: A Randomized Controlled Trial|
|Study Start Date :||August 2007|
|Primary Completion Date :||December 2009|
|Study Completion Date :||December 2009|
Placebo Comparator: 2
Other Name: celebrex
No Intervention: 1
- The patients' total amount of morphine requirement in the first 24 hour. [ Time Frame: 24 hour ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00520338
|Department of Anesthesiology, Faculty of Medicine, Siriraj Hospital, Mahidol University|
|Bangkok, Thailand, 10700|
|Principal Investigator:||Sirilak Suksompong, MD||Department of anesthesiology. Siriraj Hospital, Mahidol University, Bangkok, Thailand|