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The Finnish Diabetes Prevention Study (DPS)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified August 2011 by National Institute for Health and Welfare, Finland.
Recruitment status was:  Active, not recruiting
University of Eastern Finland
Finnish Diabetes Association
University of Oulu
Information provided by (Responsible Party):
National Institute for Health and Welfare, Finland Identifier:
First received: August 16, 2007
Last updated: August 31, 2011
Last verified: August 2011
The aim of this study is to clarify whether lifestyle intervention provided to people with high type 2 diabetes risk will lower the cumulative incidence of diabetes. Furthermore, the aim is to study the effect of lifestyle intervention on cardiovascular risk.

Condition Intervention
Type 2 Diabetes
Behavioral: Intensive lifestyle counselling

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
Official Title: The Finnish Diabetes Prevention Study: A Follow-up Study on the Effect of a Dietary and Exercise Intervention in the Prevention of Diabetes and Its Vascular Complications

Further study details as provided by National Institute for Health and Welfare, Finland:

Primary Outcome Measures:
  • Diabetes incidence [ Time Frame: During the intervention period + after the intervention has been stopped ]

Secondary Outcome Measures:
  • CVD incidence [ Time Frame: During the total follow up ]

Enrollment: 522
Study Start Date: November 1993
Estimated Study Completion Date: December 2013
Estimated Primary Completion Date: December 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
Intensive lifestyle intervention
Behavioral: Intensive lifestyle counselling

Individualized dietary and physical activity counselling aiming at

  1. weight reduction
  2. dietary fibre 15 g /1000 kcal or more
  3. energy proportion of dietary fat less than 30%
  4. energy proportion of saturated fat less than 10%
  5. moderate physical activity >30 minutes per day or 4 hours per week
No Intervention: 2
Standard counselling at baseline


Ages Eligible for Study:   40 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • impaired glucose tolerance (p-glucose 2 hours after a 75 g oral glucose load between 7.8 and 11.0 mmol/l)
  • body mass index 25 or higher

Exclusion Criteria:

  • diabetes (previous gestational diabetes accepted)
  • other chronic disease rendering survival for 6 years
  • condition or medication affecting glucose tolerance
  • recent myocardial infarction
  Contacts and Locations
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Please refer to this study by its identifier: NCT00518167

Diabetes Prevention Unit, Department of Health Promotion and Chronic Disease Prevention, National Institute for Health and Welfare
Helsinki, Finland
Department of Public Health and Clinical Nutrition, University of Eastern Finland
Kuopio, Finland
Department of Sports Medicine, Oulu Deaconess Institute
Oulu, Finland
The Diabetes Center, Finnish Diabetes Association
Tampere, Finland
Sponsors and Collaborators
National Institute for Health and Welfare, Finland
University of Eastern Finland
Finnish Diabetes Association
University of Oulu
Principal Investigator: Jaakko Tuomilehto, professor National Public Health Institute and University of Helsinki
Principal Investigator: Matti Uusitupa, professor University of Eastern Finland
  More Information


Publications automatically indexed to this study by Identifier (NCT Number):

Responsible Party: National Institute for Health and Welfare, Finland Identifier: NCT00518167     History of Changes
Other Study ID Numbers: KTL151-6
Study First Received: August 16, 2007
Last Updated: August 31, 2011

Keywords provided by National Institute for Health and Welfare, Finland:
Type 2 diabetes
primary prevention
physical activity
impaired glucose tolerance
randomized controlled study

Additional relevant MeSH terms:
Diabetes Mellitus
Diabetes Mellitus, Type 2
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases processed this record on April 28, 2017