Presence of IBD Specific Antibodies (ASCA, ALCA, ACCA, AMCA) in the Sera of Patients With Spondyloarthropathy

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00517101
Recruitment Status : Unknown
Verified August 2007 by Tel-Aviv Sourasky Medical Center.
Recruitment status was:  Not yet recruiting
First Posted : August 16, 2007
Last Update Posted : August 16, 2007
Information provided by:
Tel-Aviv Sourasky Medical Center

Brief Summary:

A relationship between IBD and spondyloarthropathy is well recognized. ASCA ( anti saccharomyces cerevisiae antibodies)are considered to be a serological marker for Crohn's disease and have been studied in patients with spondyloarthropathy with conflicting results. More recently, new serological markers for IBD have been described. These markers are antibodies to certain defined glycans , and their use may permit an improved diagnosis of IBD.

The aim of our study is to investigate wether these new serological markers are present in the sera of patients with spondyloarthropathy.

Condition or disease
Psoriatic Arthritis Ankylosing Spondylitis Undifferentiated Spondyloarthropathy

Study Type : Observational
Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
Time Perspective: Prospective
Study Start Date : September 2007

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • diagnosis of psoriatic arthritis, ankylosing spondylitis, or undifferentiated spondyloarthropathy

Exclusion Criteria:

  • diagnosed inflammatory bowel disease

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00517101

Sponsors and Collaborators
Tel-Aviv Sourasky Medical Center
Principal Investigator: valerie aloush, MD Tel-Aviv Sourasky Medical Center Identifier: NCT00517101     History of Changes
Other Study ID Numbers: TAMSC-07-VA-318-CTIL
First Posted: August 16, 2007    Key Record Dates
Last Update Posted: August 16, 2007
Last Verified: August 2007

Keywords provided by Tel-Aviv Sourasky Medical Center:
inflammatory bowel disease

Additional relevant MeSH terms:
Spondylitis, Ankylosing
Arthritis, Psoriatic
Bone Diseases, Infectious
Bone Diseases
Musculoskeletal Diseases
Spinal Diseases
Joint Diseases
Skin Diseases, Papulosquamous
Skin Diseases
Immunologic Factors
Physiological Effects of Drugs