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Genetic Abnormalities and Biological Changes of Panic Disorder Patients After Pharmacotherapy

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ClinicalTrials.gov Identifier: NCT00515996
Recruitment Status : Unknown
Verified August 2007 by Samsung Medical Center.
Recruitment status was:  Recruiting
First Posted : August 14, 2007
Last Update Posted : August 14, 2007
Sponsor:
Information provided by:

Study Description
Brief Summary:
We plan to examine genetic polymorphism of catechol-O-methyltransferase in panic disorder and neurobiological changes of panic disorder patients after 12 weeks of pharmacotherapy with paroxetine. We plan to include 40 panic disorder patients and 40 normal control subjects in this study for 3 years.

Condition or disease
Panic Disorder

Study Design

Study Type : Observational
Estimated Enrollment : 80 participants
Observational Model: Case Control
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Genetic Abnormalities and Changes of Autonomic Nervous System, Serotonin System, and Neuroendocrine System According to Pharmacotherapy in Panic Disorder
Study Start Date : January 2006
Estimated Study Completion Date : December 2008

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Panic Disorder
Drug Information available for: Serotonin
U.S. FDA Resources

Groups and Cohorts

Group/Cohort
Case: 2
paroxetine treatment group vs. normal control group


Outcome Measures

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Panic disorder

Exclusion Criteria:

  • Other major medical or psychiatric illnesses
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00515996


Locations
Korea, Republic of
Samsung Medical Center Recruiting
Seoul, Korea, Republic of, 135-710
Contact: Tae Geun Kim, BA    82-2-3410-2975    tggo.kim@samsung.com   
Principal Investigator: Bum-Hee Yu, M.D. & Ph.D.         
Sponsors and Collaborators
Samsung Medical Center
Investigators
Principal Investigator: Bum-Hee Yu, M.D. & Ph.D. Samsung Medical Center, Sungkyunkwan University School of Medicine
More Information

ClinicalTrials.gov Identifier: NCT00515996     History of Changes
Other Study ID Numbers: C-A6-418-2
First Posted: August 14, 2007    Key Record Dates
Last Update Posted: August 14, 2007
Last Verified: August 2007

Keywords provided by Samsung Medical Center:
panic disorder
paroxetine
genetic polymorphism
serotonin

Additional relevant MeSH terms:
Disease
Panic Disorder
Pathologic Processes
Anxiety Disorders
Mental Disorders
Serotonin
Serotonin Receptor Agonists
Serotonin Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs