Explanted Lung Tissues With Pulmonary Fibrosis
The goal of this study is to use the tissues from the explanted lungs in order to better study the cause of pulmonary fibrosis at a cellular level.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Utilization of Explanted Lungs for Isolation of Tissue Samples and Primary Cell Lines to Study Pulmonary Fibrosis|
- assess fibroblasts and cytokines associated with pulmonary fibrosis [ Time Frame: 12/2013 ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
explanted lung tissue
|Study Start Date:||February 2006|
|Estimated Study Completion Date:||December 2019|
|Estimated Primary Completion Date:||December 2018 (Final data collection date for primary outcome measure)|
Pulmonary Fibrosis involves scarring of the lung. Gradually, the air sacs of the lungs become replaced by fibrotic tissue. The most current thinking is that the fibrotic process is a reaction to tiny injury to the lung. When the scar forms, the tissue becomes thicker causing a permanent loss of the tissue's ability to carry oxygen into the bloodstream.
We need to obtain lung tissue from patients without pulmonary fibrosis and compare it to lung tissue from patients with pulmonary fibrosis.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00515567
|Contact: Edward Garrity, MDfirstname.lastname@example.org|
|United States, Illinois|
|The University of Chicago||Recruiting|
|Chicago, Illinois, United States, 60637|
|Contact: Janine Grohar 773-702-6156 email@example.com|
|Principal Investigator:||Edward Garrity, MD||University of Chicago|