Unrelated Stem Cell Transplantation for Adults With Hematopoietic Disorders
This study performs HLA matched stem cell transplantation from unrelated donors in adults who require stem cell transplantation but do not have a matched related donor available. The incidence of graft-versus-host disease in unrelated stem cell transplantation is recorded. This study also monitors the activity and toxicity of total body irradiation and cyclosphosphamide followed by stem cell transplantation from matched unrelated donors.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Standard of Care Trial: Unrelated Stem Cell Transplantation for Adults With Hematopoietic Disorders|
|Study Start Date:||January 1999|
|Study Completion Date:||June 2009|
|Primary Completion Date:||June 2009 (Final data collection date for primary outcome measure)|
This protocol identifies a standard-of-care method for unrelated stem cell transplantation in adults. Performing this service in a consistent and documented fashion allows investigators to obtain informed consent from recipients. Data is tabulated locally for quality-control comparisons with nationally-reported standards. As a condition of maintaining transplant center status and to have acess to NMDP-registered donors, UCSF submits clinical and outcome data to the NMDP. As a result, UCSF is contributing to the resolution of remaining uncertainties regarding particular transplantation practices.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00511537
|United States, California|
|University of California San Francisco|
|San Francisco, California, United States, 94143|
|Principal Investigator:||Thomas G. Martin, M.D.||University of California, San Francisco|