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Influence of Paternal Age on Assisted Reproduction Outcome (MALE AGING)

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ClinicalTrials.gov Identifier: NCT00510861
Recruitment Status : Completed
First Posted : August 2, 2007
Last Update Posted : April 28, 2017
Sponsor:
Information provided by:

Study Description
Brief Summary:

In the recent years, there is an increasing tendency to the parenthood delay in developed countries, and there is not enough information available regarding the influence of the male's age on fertility. If any, the negative impact should be acting at advanced ages.

Our aim with this work was to determine the role of paternal age on IUI results embryo quality and IVF outcome. Evenmore, in order to standardize the female factor, good quality oocytes (from fertile oocyte donors) and only first IVF cycles in young women were considered.


Condition or disease
We Will Retrospectively Assess Our Databases in Our Clinic Instituto Valenciano de Infertilidad in Valencia (Spain) Searching for Assisted Reproduction Procedures IUI Standard IVF/ICSI Cycles and Ovum Donation IVF/ICSI Cycles Who Were Referred to Our Unit to Cryopreserve Sperm During the Period From January 2000 to December 2006

Detailed Description:

A retrospective study has been designed with a total number of 2204 IUI, 1286 IVF cycles and 1412 IVF cycles with donated oocytes from 2000 to 2006.

The inclusion criteria will be for IUI: women under 38 years old, tubal patency demonstrated by hysterosalpingography, normal uterine scan, normal basal hormonal levels, body mass index < 27 kg/m2, and absence of polycystic ovarian syndrome and endometriosis. For normal IVF cycles and oocyte donation cycles only first cycles will be analyzed. Cycles will be studied only in couples with absence of severe male factor.


Study Design

Study Type : Observational
Time Perspective: Retrospective
Official Title: Influence of Paternal Age on Assisted Reproduction Outcome
Study Start Date : February 2007
Study Completion Date : May 2007
Groups and Cohorts


Outcome Measures

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • women under 38 years old, tubal patency demonstrated by hysterosalpingography, normal uterine scan, normal basal hormonal levels, body mass index < 27 kg/m2.

Exclusion Criteria:

  • absence of polycystic ovarian syndrome, hydrosalpinx or endometriosis.
  • Cycles were studied only in couples with absence of severe male factor.
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00510861


Locations
Spain
IVI
Valencia, Spain, 46015
Sponsors and Collaborators
Instituto Valenciano de Infertilidad, IVI VALENCIA
Investigators
Principal Investigator: Marcos Meseguer, PhD IVI Valencia
More Information

ClinicalTrials.gov Identifier: NCT00510861     History of Changes
Other Study ID Numbers: VLC-MM-0205-507-26
First Posted: August 2, 2007    Key Record Dates
Last Update Posted: April 28, 2017
Last Verified: April 2017

Keywords provided by Instituto Valenciano de Infertilidad, IVI VALENCIA:
male age, assisted reproduction, sperm, pregnancy outcome