Influence of Paternal Age on Assisted Reproduction Outcome (MALE AGING)
In the recent years, there is an increasing tendency to the parenthood delay in developed countries, and there is not enough information available regarding the influence of the male's age on fertility. If any, the negative impact should be acting at advanced ages.
Our aim with this work was to determine the role of paternal age on IUI results embryo quality and IVF outcome. Evenmore, in order to standardize the female factor, good quality oocytes (from fertile oocyte donors) and only first IVF cycles in young women were considered.
We Will Retrospectively Assess Our Databases in Our Clinic:
Instituto Valenciano de Infertilidad in Valencia (Spain)
Searching for Assisted Reproduction Procedures
(IUI, Standard IVF/ICSI Cycles and Ovum Donation IVF/ICSI Cycles)
Who Were Referred to Our Unit to Cryopreserve Sperm During the Period
From January 2000 to December 2006.
|Study Design:||Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Cross-Sectional
Time Perspective: Retrospective
|Official Title:||Influence of Paternal Age on Assisted Reproduction Outcome|
|Study Start Date:||February 2007|
|Study Completion Date:||May 2007|
A retrospective study has been designed with a total number of 2204 IUI, 1286 IVF cycles and 1412 IVF cycles with donated oocytes from 2000 to 2006.
The inclusion criteria will be for IUI: women under 38 years old, tubal patency demonstrated by hysterosalpingography, normal uterine scan, normal basal hormonal levels, body mass index < 27 kg/m2, and absence of polycystic ovarian syndrome and endometriosis. For normal IVF cycles and oocyte donation cycles only first cycles will be analyzed. Cycles will be studied only in couples with absence of severe male factor.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00510861
|Valencia, Spain, 46015|
|Principal Investigator:||Marcos Meseguer, PhD||IVI Valencia|