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Non-prescription Versus Prescription Topical Treatments Versus no Treatment in the Control of Sweating

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ClinicalTrials.gov Identifier: NCT00509886
Recruitment Status : Completed
First Posted : August 1, 2007
Last Update Posted : November 10, 2014
Sponsor:
Information provided by:
Northwestern University

Brief Summary:
The purpose of this study is to assess the effectiveness of the prescription treatment compared to the non-prescription treatment. It is hypothesized that the prescription treatment will have a significantly greater effect than the non-prescription treatment on decreasing excess sweating.

Condition or disease Intervention/treatment Phase
Hyperhidrosis Excess Sweating Drug: Drysol Drug: Drioff Not Applicable

Detailed Description:
The objective of this study is to assess the effectiveness of the prescription treatment compared to the non-prescription treatment. It is hypothesized that the prescription treatment will have a significantly greater effect than the non-prescription treatment on decreasing excess sweating.

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 24 participants
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Prevention
Official Title: Non-prescription Versus Prescription Topical Treatments Versus no Treatment in the Control of Sweating
Study Start Date : June 2007
Actual Primary Completion Date : August 2007
Actual Study Completion Date : August 2007

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arm Intervention/treatment
Experimental: 1
ARMs were randomized. One side of the body received treatment with one antiperspirant and the contralateral side with a different antiperspirant.
Drug: Drysol
20% aluminum chloride hexahydrate
Experimental: 2
ARMs were randomized. One side of the body received treatment with one antiperspirant and the contralateral side with a different antiperspirant.
Drug: Drioff
1% aluminum acetate



Primary Outcome Measures :
  1. Gravimetric analysis [ Time Frame: 3 hours ]

Secondary Outcome Measures :
  1. Subject sweat assessment [ Time Frame: 3 hours ]
  2. HDSS [ Time Frame: 3 hours ]


Information from the National Library of Medicine

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Ages Eligible for Study:   21 Years to 30 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • age 21-30 years
  • males and females
  • The subjects are in good health.
  • The subjects have willingness and the ability to understand and provide informed consent for participation in the study.

Exclusion Criteria:

  • Subjects with primary hyperhidrosis
  • Subjects who are unable to withstand prolonged heat exposure or who have self-reported history of cardiovascular or respiratory disorders.
  • Subjects who are unable to give informed consent.
  • Subjects with mental illness.
  • Subjects who are pregnant or nursing.
  • Subjects with systemic or local skin disease and/or infection that may interfere with the conduct of the study.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00509886


Locations
United States, Illinois
Northwestern University Dermatology
Chicago, Illinois, United States, 60611
Sponsors and Collaborators
Northwestern University
Investigators
Principal Investigator: Murad Alam, MD Northwestern University dermatology
Study Director: Dennis West, PhD Northwestern University dermatology

Responsible Party: Murad Alam, MD, Northwestern University Dermatology department
ClinicalTrials.gov Identifier: NCT00509886     History of Changes
Other Study ID Numbers: STU00000722
First Posted: August 1, 2007    Key Record Dates
Last Update Posted: November 10, 2014
Last Verified: November 2014

Additional relevant MeSH terms:
Hyperhidrosis
Sweat Gland Diseases
Skin Diseases