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Non-prescription Versus Prescription Topical Treatments Versus no Treatment in the Control of Sweating

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00509886
First Posted: August 1, 2007
Last Update Posted: November 10, 2014
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Northwestern University
  Purpose
The purpose of this study is to assess the effectiveness of the prescription treatment compared to the non-prescription treatment. It is hypothesized that the prescription treatment will have a significantly greater effect than the non-prescription treatment on decreasing excess sweating.

Condition Intervention
Hyperhidrosis Excess Sweating Drug: Drysol Drug: Drioff

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Prevention
Official Title: Non-prescription Versus Prescription Topical Treatments Versus no Treatment in the Control of Sweating

Resource links provided by NLM:


Further study details as provided by Northwestern University:

Primary Outcome Measures:
  • Gravimetric analysis [ Time Frame: 3 hours ]

Secondary Outcome Measures:
  • Subject sweat assessment [ Time Frame: 3 hours ]
  • HDSS [ Time Frame: 3 hours ]

Enrollment: 24
Study Start Date: June 2007
Study Completion Date: August 2007
Primary Completion Date: August 2007 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
ARMs were randomized. One side of the body received treatment with one antiperspirant and the contralateral side with a different antiperspirant.
Drug: Drysol
20% aluminum chloride hexahydrate
Experimental: 2
ARMs were randomized. One side of the body received treatment with one antiperspirant and the contralateral side with a different antiperspirant.
Drug: Drioff
1% aluminum acetate

Detailed Description:
The objective of this study is to assess the effectiveness of the prescription treatment compared to the non-prescription treatment. It is hypothesized that the prescription treatment will have a significantly greater effect than the non-prescription treatment on decreasing excess sweating.
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   21 Years to 30 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • age 21-30 years
  • males and females
  • The subjects are in good health.
  • The subjects have willingness and the ability to understand and provide informed consent for participation in the study.

Exclusion Criteria:

  • Subjects with primary hyperhidrosis
  • Subjects who are unable to withstand prolonged heat exposure or who have self-reported history of cardiovascular or respiratory disorders.
  • Subjects who are unable to give informed consent.
  • Subjects with mental illness.
  • Subjects who are pregnant or nursing.
  • Subjects with systemic or local skin disease and/or infection that may interfere with the conduct of the study.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00509886


Locations
United States, Illinois
Northwestern University Dermatology
Chicago, Illinois, United States, 60611
Sponsors and Collaborators
Northwestern University
Investigators
Principal Investigator: Murad Alam, MD Northwestern University dermatology
Study Director: Dennis West, PhD Northwestern University dermatology
  More Information

Responsible Party: Murad Alam, MD, Northwestern University Dermatology department
ClinicalTrials.gov Identifier: NCT00509886     History of Changes
Other Study ID Numbers: STU00000722
First Submitted: July 31, 2007
First Posted: August 1, 2007
Last Update Posted: November 10, 2014
Last Verified: November 2014

Additional relevant MeSH terms:
Hyperhidrosis
Sweat Gland Diseases
Skin Diseases