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The Mechanism of Melanocyte Self-Assembly on Biomaterials and the Functional Analysis

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ClinicalTrials.gov Identifier: NCT00509314
Recruitment Status : Unknown
Verified May 2006 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
First Posted : July 31, 2007
Last Update Posted : July 31, 2007
Sponsor:
Collaborators:
Information provided by:

Study Description
Brief Summary:
The aim of this study is to survey melanocytes in the ability of self-assembly on biomaterials and functional analysis in vitro. Also, this study may provide a better way for treatment of vitiligo after understanding the functional aspects of melanocytes.

Condition or disease Intervention/treatment
Melanocyte Vitiligo Behavioral: melanocyte self-assembly and functional analysis

Detailed Description:
Vitiligo is a chronic disease that causes loss of melanocyte and pigment of the skin. Traditional treatments for vitiligo including topical corticosteroids and phototherapy lead to limited clinical effects. Autologous melanocyte transplantation is another way to treat vitiligo. However, the effect is largely affected by whether cultivated melanocytes are successfully uptaken by vitiliginous skin. The aim of this study is to survey the self-assembly on biomaterials and functional analysis. In the long run, this study may provide a better way for treatment of vitiligo.

Study Design

Study Type : Observational
Estimated Enrollment : 400 participants
Observational Model: Natural History
Time Perspective: Cross-Sectional
Time Perspective: Prospective
Official Title: The Mechanism of Melanocyte Self-Assembly on Biomaterials and the Functional Analysis
Study Start Date : May 2006
Estimated Study Completion Date : December 2016

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Vitiligo
U.S. FDA Resources

Groups and Cohorts


Outcome Measures

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Patients receiving cosmetic removal of moles

Exclusion Criteria:

  • No special exclusion criteria
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00509314


Contacts
Contact: Sung-Jan Lin, MD PhD +886-2-23123456 ext 5323 jsjl2000tw@yahoo.com.tw

Locations
Taiwan
National Taiwan University Hospital Recruiting
Taipei, Taiwan, 100
Contact: Sung-Jan Lin, MD PhD    +886-2-23123456 ext 5323    jsjl2000tw@yahoo.com.tw   
Principal Investigator: Sung-Jan Lin, MD PhD         
Sponsors and Collaborators
National Taiwan University Hospital
National Science Council, Taiwan
National Health Research Institutes, Taiwan
Investigators
Principal Investigator: Sung-Jan Lin, MD PhD National Taiwan University Hospital