Evaluating the Occurence of New and Progression of Existing Peripheral Venous Disease in Leg Veins
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|ClinicalTrials.gov Identifier: NCT00508079|
Recruitment Status : Completed
First Posted : July 27, 2007
Last Update Posted : July 12, 2013
|Condition or disease|
|Peripheral Vascular Diseases|
Peripheral venous disease is a general term for damage, defects, or blockage that occurs in the peripheral veins, which carry blood from the hands and feet back to the heart to receive oxygen. The most common cause of peripheral venous disease is a blood clot that blocks a vein. Varicose veins, which are swollen blood vessels near the surface of the skin, and chronic venous insufficiency, a condition in which blood in the leg veins does not drain properly, are two other common types of peripheral venous disease. From 1996 to 2000, the San Diego Population Study (SDPS) evaluated a group of individuals to gather information on the prevalence of venous disease. This current study will re-evaluate the SDPS participants to document changes that have occurred in their leg veins over the past 11 years, including any new venous disease and any progression of existing venous disease. Study researchers will also evaluate how venous disease relates to risk factors, symptoms, and quality of life issues.
This study will enroll people who participated in the SDPS study. Each participant will attend one study visit. Study staff will conduct a 1-hour interview with each participant to collect information on their medical history, disease-related symptoms, risk factors for venous disease, family health history, health habits, and quality of life. Blood collection will occur, participant's leg veins will be examined and photographed, and blood flow in the legs will be measured with an ultrasound.
|Study Type :||Observational|
|Actual Enrollment :||1103 participants|
|Official Title:||Incidence and Progression of Peripheral Venous Disease|
|Study Start Date :||July 2007|
|Actual Primary Completion Date :||January 2011|
|Actual Study Completion Date :||January 2011|
- Incident Venous Disease [ Time Frame: Since previous visit (approximately 11 years) ]
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00508079
|United States, California|
|University of California San Diego|
|La Jolla, California, United States, 92093|
|Principal Investigator:||Michael H. Criqui, MD, MPH||University of California, San Diego|