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Hemodynamic Parameters in Euthyroid Patients With Thyroid Nodules

This study has been terminated.
(The received reliability with increase in quantity of participants of research did not vary)
Information provided by:
Yaroslavl State Medical Academy Identifier:
First received: July 25, 2007
Last updated: February 6, 2008
Last verified: February 2008
The purpose of this study is to determine the relationship of hemodynamic parameters with the level of thyroid hormones and the histological structure of thyroid nodules in euthyroid patients.

Thyroid Nodules

Study Type: Observational
Study Design: Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by Yaroslavl State Medical Academy:

Estimated Enrollment: 100
Study Completion Date: December 2007
Cohort: Patients with normal blood pressure scheduled to have thyroid nodules surgically removed
Patients from group A not receiving any drugs and who lack other pathology, gender and age matched group B1
Cohort: Patients with increased blood pressure scheduled to have thyroid nodules surgically removed
Patients from group B not receiving any drugs and who lack other pathology, gender and age matched group A1

Detailed Description:

As opposed to widely investigated condition of cardiovascular system in patients with functional disorders of thyroid gland, the relationship between thyroid hormones and hemodynamic parameters in euthyroid patients remains not enough clear.

We detect the parameters of blood pressure and thyroid hormones in euthyroid patients with thyroid nodules directly before planned operation on the thyroid gland.

As the study is carries out directly before operation, that assumes presence of preoperative stress in patients, activity of the sympatho - adrenal system is estimated in addition.

On the one hand, the design of our research will allow to estimate relationship of thyroid hormones with the parameters of blood pressure in conditions of euthyroidism, on the other hand - to investigate features of blood pressure in patients with thyroid nodules.

The research of the patients in the preoperative period will enable to select the group of patients without pathology of cardiovascular system whose increased blood pressure is connected with preoperative stress, that in turn will allow to exclude influence of the pathology of the cardiovascular system on studied correlation.


Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Euthyroid patients with thyroid nodules before operation on the thyroid gland

Exclusion Criteria:

  • Hyperthyroidism
  • Hypothyroidism
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Please refer to this study by its identifier: NCT00507897

Russian Federation
Yaroslavl State Medical Academy
Yaroslavl, Russian Federation, 150000
Sponsors and Collaborators
Yaroslavl State Medical Academy
Study Chair: Yuriy Alexandrov, Professor Yaroslavl State Medical Academy
  More Information Identifier: NCT00507897     History of Changes
Other Study ID Numbers: ESheverdova-1
Study First Received: July 25, 2007
Last Updated: February 6, 2008

Keywords provided by Yaroslavl State Medical Academy:
thyroid nodules, blood pressure, thyroid hormones

Additional relevant MeSH terms:
Thyroid Diseases
Thyroid Nodule
Endocrine System Diseases
Thyroid Neoplasms
Endocrine Gland Neoplasms
Neoplasms by Site
Head and Neck Neoplasms processed this record on April 26, 2017