Blood Collection From Individuals With Lung Disease for Genetic Studies (Qatar) (Q-BC)
Interstitial Lung Disease
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Collection of Blood for Gene Expression Study in Individuals With Chronic Lung Diseases (Qatar)|
|Study Start Date:||May 2006|
|Study Completion Date:||May 2012|
1: Lung Disease
Individuals with at least one of the following: (1) symptoms consistent with pulmonary disease; (2) chest X-ray consistent with lung disease; (3) pulmonary function tests consistent with lung disease; (4) lung biopsy consistent with lung disease; (5) family history of lung disease; (6) patients with diseases of organs with known association with lung disease; and (7) individuals suspected of history of lung diseased based on history and/or physical examination
2: Normal Control
Individuals without a history of lung disease.
This protocol is designed to collect a small amount of blood for extraction of DNA (genetic material) for the study of the genetic basis of lung disease. The study population will include individuals with known lung diseases and controls without lung disease. Individuals in the study population will be individuals at the Hamad Medical Corporation, Qatar (HMC), as well as other individuals recruited for this study. In this protocol, researchers will survey medical records of patients with chronic lung disease, in order to study the clinical characteristics of these individuals, and the researchers will collect blood to evaluate the genetic characteristics of individuals with chronic lung diseases including asthma, and COPD (chronic obstructive pulmonary disease), pulmonary fibrosis, and lung cancer. The researchers will also collect blood samples of individuals without lung disease to serve as control.
This protocol, to be carried out at Weill Cornell Medical College - Qatar and Hamad Medical Corporation, Qatar, parallels a similar approved protocol IRB #0508008095, entitled, "Collection of Blood for Gene Expression/Genomic Studies in Individuals with Chronic Lung Diseases", ongoing at Weill Cornell Medical College - New York.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00504361
|Hamad Medical Corporation|
|Principal Investigator:||Ronald G Crystal, MD||Weill Cornell Medical College, NY and Qatar|