Uterine Flora During Elective and Urgent Cesarean Sections

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00500019
Recruitment Status : Completed
First Posted : July 12, 2007
Last Update Posted : March 31, 2009
Information provided by:
Western Galilee Hospital-Nahariya

Brief Summary:
Hypothesis: The bacterial flora of the uterus during elective Cesarean sections differs from the uterine flora during non-elective Cesarean sections. We want to study whether the uterine flora can predict post-cesarean febrile morbidity and endometritis.

Condition or disease

Detailed Description:

Objective: To evaluate the uterine flora at the time of elective and non-elective cesarean sections and to study the relationship to the development of postpartum fever and/or endometritis.

Methods: Eight-hundred women who will be delivered by cesarean section will be enrolled in this study. Cultures will be obtained during the surgery from the open uterine cavity after removal of the placenta. Data regarding postpartum morbidity would be collected.

Study Type : Observational
Estimated Enrollment : 600 participants
Time Perspective: Prospective
Official Title: Uterine Flora During Elective and Urgent Cesarean Sections and Its Relationship to Postpartum Complications.
Study Start Date : January 2005
Actual Study Completion Date : September 2008

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Cesarean Section
U.S. FDA Resources

Elective Cesarean sections
Non-elective cesarean section

Primary Outcome Measures :
  1. To compare bacteriological growth between elective and non-elective cesarean section [ Time Frame: 5 years ]

Secondary Outcome Measures :
  1. To study the various bacteria growth in the uteri, and to compare type of bacteria to post-op morbidity [ Time Frame: 5 years ]

Biospecimen Retention:   Samples Without DNA
Uterine bacteriological cultures

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 50 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Women undergoing cesarean sections in Western galilee Hospital

Inclusion Criteria:

  • Cesarean delivery

Exclusion Criteria:

  • Vaginal delivery

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00500019

Western Galilee Hospital
Nahariya, Israel, 22100
Sponsors and Collaborators
Western Galilee Hospital-Nahariya
Principal Investigator: Ido Solt, MD Western Galilee Hospital

Responsible Party: Professor Jacob Bornstein, Department Obstetrics & Gynecology, Western Galilee Hospital, Nahariya, Israel Identifier: NCT00500019     History of Changes
Other Study ID Numbers: 1-Bornstein
First Posted: July 12, 2007    Key Record Dates
Last Update Posted: March 31, 2009
Last Verified: March 2009

Additional relevant MeSH terms:
Pelvic Inflammatory Disease
Adnexal Diseases
Genital Diseases, Female
Uterine Diseases