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The Prognostic Value of Interim PET/CT After 2 Cycles of Chemotherapy in Predicting Progression of Non Hodgkins Lymphoma

This study has been withdrawn prior to enrollment.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00498667
First Posted: July 10, 2007
Last Update Posted: May 6, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
e_dann, Rambam Health Care Campus
  Purpose
A retrospective analysis will be performed regarding the usefulness of PET/CT performed following 2 cycle of chemotherapy in evaluation of progression, free survival and overall survival of patients with aggressive non Hodgkin Lymphoma.

Condition
Lymphoma; Large Cell (Diffuse) With Small Cell, Diffuse

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Evaluation of the Prognostic Value of Early Interim PET/CT for Prediction of Progression Free Survival of Patients With Aggressive B Cells Non Hodgkin Lymphoma

Resource links provided by NLM:


Further study details as provided by e_dann, Rambam Health Care Campus:

Primary Outcome Measures:
  • progression free survival [ Time Frame: 5 years ]

Biospecimen Retention:   None Retained
no biopsies are to be retained

Enrollment: 0
Study Start Date: December 2006
Study Completion Date: December 2014
Primary Completion Date: December 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts
PET/CT
all patients with aggressive lymphoma who had a baseline and interim pet/ct study

Detailed Description:
Patients who were treated for aggressive non-Hodgkin lymphoma with adriamycin containing regimen, CHOP and High dose CHOP with or without rituximab were evaluated post 2 cycles of chemotherapy to rule out disease progression . Currently a retrospective evaluation of PET/CT as a predictive value for progression free survival and overall survival is evaluated
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
all patients with agressive non hodgkin lymphoma who had interim pet/ct during therapy
Criteria

Inclusion Criteria:

  • aggressive non-Hodgkin lymphoma b cells
  • age 18-70
  • bilirubin less then 2
  • creatinine less then 2
  • Pet/CT performed post 2 cycles

Exclusion Criteria:

  • no PET/CT post 2 cycles performed
  • bilirubin >2
  • creatinine more then 2
  • HIV positivity
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00498667


Locations
Israel
RAMBAM health care Campus
Haifa, Israel, 31096
Sponsors and Collaborators
Rambam Health Care Campus
Investigators
Principal Investigator: Eldad J Dann, MD RAMBAM health care campus,Rappaport faculty of medicine Technion Israel Technical institute
  More Information

Responsible Party: e_dann, Prof Eldad Dann, Rambam Health Care Campus
ClinicalTrials.gov Identifier: NCT00498667     History of Changes
Other Study ID Numbers: cc-NHL2615_CTIL
First Submitted: July 8, 2007
First Posted: July 10, 2007
Last Update Posted: May 6, 2015
Last Verified: May 2015

Keywords provided by e_dann, Rambam Health Care Campus:
PET/CT
Aggressive non-Hodgkin Lymphoma

Additional relevant MeSH terms:
Lymphoma
Lymphoma, Non-Hodgkin
Lymphoma, Large B-Cell, Diffuse
Neoplasms by Histologic Type
Neoplasms
Lymphoproliferative Disorders
Lymphatic Diseases
Immunoproliferative Disorders
Immune System Diseases
Lymphoma, B-Cell