Anisometropia Amblyopia Improved by Perceptual Learning and Patching

This study has been completed.

Sponsor:

Information provided by:

Tri-Service General Hospital

ClinicalTrials.gov Identifier:

NCT00498641

First received: July 9, 2007

Last updated: NA

Last verified: July 2007

History: No changes posted

Purpose

To compare the effects of perceptual learning with patching on improving visual acuity and contrast sensitivity in payient with anisometropic amblyopia.

Condition	Intervention	Phase
Anisometropic Amblypia	Procedure: computer program and patching	Phase 3


Study Type:	Interventional
Study Design:	Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Parallel Assignment Masking: Single Blind Primary Purpose: Treatment

Resource links provided by NLM:

MedlinePlus related topics: Amblyopia

U.S. FDA Resources

Further study details as provided by Tri-Service General Hospital:

Primary Outcome Measures:

Corrected amblyopic logMAR visual acuity and contrast sensitivity function


Study Start Date:	January 2005
Study Completion Date:	January 2007

Detailed Description:

Patients with anisometropic amblyopia were randomized to patching or perceptual learning group. Corrected amblyopic logMAR visual acuity and contrast sensitivity function were measured at four-weekly intervals until visual acuity stabilized or amblyopia resolved. Improvement in visual acuity, contrast sensitivity, and the resolution of amblyopia were compared between groups.

Eligibility


Ages Eligible for Study:	3 Years to 55 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Anisometropia without strabismus
An interocular acuity difference of at least 0.2 logMAR in children (3–7 years of age) or in older children and adult patients without a history of patching or atropine penalization
All patients wore their spectacle at least one year

Exclusion Criteria:

A history of prior spectacle correction
A history of patching or optical penalization
The existence of an ocular disease that could contribute to decreased visual acuity
Learning difficulties
The presence of strabismus

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00498641

Sponsors and Collaborators

Tri-Service General Hospital

Investigators


Study Director:	Po Chen, MD	Tri-Service General Hospital

More Information

No publications provided


ClinicalTrials.gov Identifier:	NCT00498641 History of Changes
Other Study ID Numbers:	094-05-0112
Study First Received:	July 9, 2007
Last Updated:	July 9, 2007
Health Authority:	Taiwan: Institutional Review Board

Keywords provided by Tri-Service General Hospital:


perceptual learning occlusion therapy

ClinicalTrials.gov processed this record on February 27, 2015

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