Gastrointestinal Evaluation in Young Men With Iron Deficiency Anemia
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ClinicalTrials.gov Identifier: NCT00498511
Recruitment Status : Unknown
Verified June 2007 by Assaf-Harofeh Medical Center. Recruitment status was: Not yet recruiting
Both upper gastrointestinal endoscopy and colonoscopy are recommended in men and post-menopausal women with iron deficiency anemia. Due to lack of data on the yield of these endoscopies in young men, they are currently investigated as older men. The aim of this study is to evaluate prospectively the prevalence of various gastrointestinal lesions in young men with iron deficiency anemia. Our hypothesis is that the diagnostic yield of colonoscopy in young anemic men without gastrointestinal symptoms is very low, especially if a potential lesion is detected during upper gastrointestinal endoscopy. Therefore, this study will try to identify predicting factors regarding the yield of both endoscopies. Another purpose is to evaluate the outcome of patients with negative endoscopic results, during a follow-up of two years.
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Ages Eligible for Study:
18 Years to 40 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Men < 40 years old of age with iron deficiency.
hemoglobin level less than 13 gr/dl documented during the 2 years prior to entering the study with one of the following: 1) iron level less than 45 μg /dl and transferrin saturation less than 10%; 2) ferritin level less than 20 μg/L (both documented during the 4 months prior to entering the study).
Previously diagnosed disease that explain iron deficiency anemia
Colonoscopy performed during the last 4 years
Upper gastrointestinal endoscopy performed during the last 2 years