Magnetic Resonance Imaging of Atrial Septal Defects
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|ClinicalTrials.gov Identifier: NCT00498446|
Recruitment Status : Completed
First Posted : July 10, 2007
Last Update Posted : June 19, 2013
|Condition or disease|
|Atrial Septal Defect|
Background: Atrial septal defect (ASD) flow can be measured indirectly by velocity-encoded cardiovascular magnetic resonance (veCMR) of the pulmonary artery and aorta (Qp/Qs). Imaging the secundum ASD en face could potentially enable direct flow measurement and, additionally, provide valuable information regarding ASD size, shape, location, and proximity to other structures.
Methods: Patients referred for possible transcatheter ASD closure underwent a comprehensive standard evaluation including transesophageal and/or intracardiac echocardiography (ICE), and invasive oximetry. CMR was performed in parallel and included direct en face veCMR after an optimal double-oblique imaging plane was determined accounting for ASD flow direction and cardiac-cycle interatrial septal motion.
We hypothesized that En face veCMR using an optimized imaging plane can accurately determine ASD flow, size, and morphology, and that it would provide information incremental to comprehensive standard evaluation.
|Study Type :||Observational|
|Actual Enrollment :||44 participants|
|Official Title:||Imaging of Atrial Septal Defects by Velocity Encoded Cardiovascular Magnetic Resonance|
|Study Start Date :||July 2002|
|Study Completion Date :||July 2004|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00498446
|United States, North Carolina|
|Duke Cardiovascular Magnetic Resonance Center|
|Durham, North Carolina, United States, 27710|
|Principal Investigator:||Raymond J Kim, MD||Duke Cardiovascular Magnetic Resonance Center|