The Protocol of Enhanced Recovery After Surgery in Colorectal Surgery (ERAS)
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|ClinicalTrials.gov Identifier: NCT00498290|
Recruitment Status : Unknown
Verified March 2009 by Fudan University.
Recruitment status was: Recruiting
First Posted : July 10, 2007
Last Update Posted : March 25, 2009
|Condition or disease||Intervention/treatment||Phase|
|Colorectal Surgery||Procedure: enhanced recovery after surgery (ERAS) protocol Procedure: control||Not Applicable|
The key factors that keep a patient in hospital after uncomplicated major colorectal surgery include the need for parenteral analgesia(persistent pain), intravenous fluids (persistent gut dysfunction), and bed rest (persistent lack of mobility). These factors often overlap and interact to delay return of function. Obviously, postoperative complications will also prolong the time until recovery and ultimately length of stay. A clinical pathway, called Enhanced Recovery After Surgery(ERAS), to accelerate recovery after colonic resection based on a multimodal programme with optimal pain relief, stress reduction with regional anaesthesia, early enteral nutrition and early mobilisation has demonstrated improvements in physical performance, pulmonary function, body composition and a marked reduction of length of stay.
Comparison(s): A total of 500 cases colorectal surgery were randomized to receive ERAS protocol or the traditional protocol, such as mechanical bowl preparation, intravenous fluids until bowl movement recovery and bed rest.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||500 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||The Protocol of Enhanced Recovery After Surgery in Colorectal Surgery|
|Study Start Date :||September 2006|
|Actual Primary Completion Date :||February 2009|
|Estimated Study Completion Date :||March 2010|
received enhanced recovery after surgery (ERAS) protocol in colorectal surgery
Procedure: enhanced recovery after surgery (ERAS) protocol
An integrated protocol aims to allow patients to recover more quickly from major surgery, avoid medium-term sequelae of conventional postoperative care (e.g. decline in nutritional status and fatigue) and reduce health care costs by reducing hospital stay
No Intervention: B
normal recovery protocol in colorectal surgery
normal recovery protocol as usually
- safety of the ERAS protocol and whether it can decrease surgical stress, increase functional recovery and reduce complication rate in colorectal surgery [ Time Frame: perioperation and until 30 days after surgery ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00498290
|Study Chair:||jianmin xu, professor||department of general surgery, zhongshan hospital, fudan university|