Quantitative Diffusion and Fat Imaging of the Spine
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|ClinicalTrials.gov Identifier: NCT00498277|
Recruitment Status : Completed
First Posted : July 10, 2007
Last Update Posted : August 1, 2012
The purpose of this study is to determine whether or not combined quantitative diffusion and fat MR imaging techniques can differentiate between benign and malignant vertebral fractures.
|Condition or disease||Intervention/treatment|
|Osteoporosis||Procedure: Magnetic Resonance Imaging|
Researchers believe that they may be able to use MRI scans to tell if fractures of the bones in the spine are due to cancer. They believe this can be done by looking at MRIs of diffusion (the random motion of molecules) and fat. For benign and malignant processes, either diffusion or fat, or both of them, can be different, because the cell density (which affects diffusion) and bone marrow content (which affects fat) are expected to be different.
All patients in this study will have already been scheduled for MRI exams of the spine at UTMDACC.
You will have one extra MRI sequence done to look for relative fat, and a second extra MRI sequence done to look for the diffusion. The extra time required for the study should be less than 10 minutes, and the total imaging time should fall within a standard MRI time slot.
Available data from your medical record, including imaging data, will be used to set up guidelines and clear examples for checking spinal fractures.
This is an investigational study. A total of 48 patients will take part in the study. All will be enrolled at UTMDACC.
|Study Type :||Observational|
|Actual Enrollment :||21 participants|
|Official Title:||Quantitative Diffusion and Fat Imaging of Vertebral Fractures|
|Study Start Date :||August 2004|
|Actual Primary Completion Date :||July 2009|
|Actual Study Completion Date :||July 2009|
Procedure: Magnetic Resonance Imaging
One MRI sequence done to look for relative fat, and a second extra MRI sequence done to look for the diffusion.
Other Name: MRI
- MRIs of diffusion (the random motion of molecules) and fat [ Time Frame: One extra 10 minute MRI sequence during scheduled spine exam. ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00498277
|United States, Texas|
|U.T.M.D. Anderson Cancer Center|
|Houston, Texas, United States, 77030|
|Principal Investigator:||Jingfei Ma, PhD||M.D. Anderson Cancer Center|