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A Randomized Controlled Trial on the Effect of Exercise on Physical, Cognitive and Affective Function in Dementia Subjects

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ClinicalTrials.gov Identifier: NCT00497822
Recruitment Status : Unknown
Verified July 2010 by Hospital Authority, Hong Kong.
Recruitment status was:  Recruiting
First Posted : July 9, 2007
Last Update Posted : July 7, 2010
Information provided by:
Hospital Authority, Hong Kong

Brief Summary:

Studies have shown conflicting results of the effect of exercise on dementia patients.

The aim of this study is to examine the role of physical activity on the risk of cognitive impairment and dementia in older persons.

To promote the benefits of aerobic exercise on dementia patients and encourage exercise prescription in the management of dementia subjects.

Condition or disease Intervention/treatment
Dementia Procedure: Aerobic exercise training

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 64 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single
Official Title: To Study the Effect of Exercise Training in Term of Aerobic Exercise for 3 Months, on the Physical, Cognitive and Affective Function in Dementia Subjects
Study Start Date : January 2006
Estimated Study Completion Date : October 2007

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Primary Outcome Measures :
  1. Physical function measurement using SF-12 [ Time Frame: every 3 months for 1 year ]
  2. Affective function measurement by Cornell depression score [ Time Frame: every 3 months for 1 year ]
  3. Cognitive function by MMSE and ADAS-cog [ Time Frame: every 3 months for 1 year ]

Secondary Outcome Measures :
  1. 6 minutes walk, functional reach, Berg balance scale [ Time Frame: every 3 months for 1 year ]
  2. Carer stress scale [ Time Frame: every 3 months for 1 year ]
  3. No. of fall/restricted activity days/time spend in exercise or walking [ Time Frame: every 3 months for 1 year ]

Information from the National Library of Medicine

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Ages Eligible for Study:   60 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All

Inclusion Criteria:

  • MMSE<26
  • Age >60
  • Community dwelling and ambulatory
  • Have a caregiver that is willing to participate and escort patient to hospital for training and assessment

Exclusion Criteria:

  • MMSE<10
  • live in old age home
  • poor mobility, unable to attend exercise training
  • no carer to bring patient to attend hospital training

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00497822

Contact: Doris KY Miu, Dr (852) 3517 5326 donnamiu@hotmail.com

Kwong Wah Hospital Recruiting
Hong Kong, China
Sub-Investigator: Ying Fai Mak, Dr         
Sponsors and Collaborators
Hospital Authority, Hong Kong
Principal Investigator: Doris KY Miu, Dr Department of Medicine and Geriatrics, Kwong Wah Hospital

Additional Information:
ClinicalTrials.gov Identifier: NCT00497822     History of Changes
Other Study ID Numbers: KW/EX05-090
First Posted: July 9, 2007    Key Record Dates
Last Update Posted: July 7, 2010
Last Verified: July 2010

Keywords provided by Hospital Authority, Hong Kong:

Additional relevant MeSH terms:
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurocognitive Disorders
Mental Disorders