Genes Causing Ebstein's Anomaly
|ClinicalTrials.gov Identifier: NCT00497705|
Recruitment Status : Completed
First Posted : July 9, 2007
Last Update Posted : July 2, 2017
This study will investigate Ebstein's anomaly, a congenital abnormality of the tricuspid valve of the heart and try to identify the genetic origins of the disease.
Adults and children 2 years of age and older with Ebstein's anomaly and healthy volunteers may be eligible for this study. Participants undergo the following procedures:
- Blood tests: Three tube of blood will be collected, with the total amount limited to about half a teaspon for each two pounds of body weight.
- Saliva sample collection: A small amount of saliva is collected by spitting into a sterile container.
- Oral (cheek) swab: Cells are collected from the mouth using a soft brush to swab the inside lining of the cheek.
- Electrocardiogram: The electrical activity of the heart is recorded using electrodes placed on the chest.
- Echocardiogram: Heart function is assessed using ultrasound.
|Condition or disease|
|Heart Septal Defects, Ventricle Heart Defects, Congenital Double Outlet Right Ventricle Truncus Arteriosus, Persistent|
|Study Type :||Observational|
|Official Title:||Genes Causing Congenital Ebstein's Anomaly|
|Study Start Date :||July 3, 2007|
|Primary Completion Date :||July 7, 2009|
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00497705
|United States, Maryland|
|National Institutes of Health Clinical Center, 9000 Rockville Pike|
|Bethesda, Maryland, United States, 20892|
|Republican Scientific and Clinical Cardiology Center|
|Republic of Belarus, Belarus|
|Amosov Institute of Cardiovascular Surgery|