The Effect of Radiation on Semen Quality and Fertility in Men With Prostate Cancer
Recruitment status was Not yet recruiting
Many younger men are diagnosed with prostate cancer. These patients are often choosing radiation therapy as their primary treatment. The effect of this therapy on fertility will have a direct impact on their decision about therapeutic options and fertility preservation. The researchers hypothesize that when patients are treated with radiation for localized prostate cancer, infertility can occur due to direct damage to seminiferous tubules affecting sperm quality.
|Study Design:||Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
|Official Title:||The Effect of Radiation on Semen Quality and Fertility in Men Treated With External Beam Radiation or Brachytherapy for Early Stage Prostate Cancer|
|Study Start Date:||July 2007|
|Estimated Study Completion Date:||January 2008|
Prostate cancer is the most common malignant disease among men. Many young men are diagnosed with localized prostate cancer. Some of these men are choosing to manage their prostate cancer with radiation therapy. The radiation therapy delivers minimal dose exposure to adjacent organs. We hypothesize that when patients are treated with radiation therapy for localized prostate cancer, decreased fertility can occur due to damage of seminiferous tubules, which may affect sperm quality. This study will assess the impact of radiation therapy on semen and seminal fluid.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00496249
|Contact: Sally Fairbairn, BSc||416 946 4501 ext firstname.lastname@example.org|
|Contact: Karen Hersey, RN||416 946 email@example.com|
|University Health Network||Not yet recruiting|
|Toronto, Ontario, Canada, M5G 2M9|
|Principal Investigator:||Neil Fleshner, MD||University Health Network, Toronto|