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Cognitive Therapy to Improve Word Finding

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ClinicalTrials.gov Identifier: NCT00494520
Recruitment Status : Completed
First Posted : June 29, 2007
Last Update Posted : September 19, 2017
Sponsor:
Information provided by (Responsible Party):
Georgetown University

Brief Summary:
Adults who sustain brain damage due to stroke, traumatic injury or surgery may develop difficulty finding words. This study compares the effectiveness of two behavior-based programs to improve picture naming ability in these individuals.

Condition or disease Intervention/treatment
Anomia Aphasia Traumatic Brain Injury Cerebrovascular Accident Procedure: Errorful training condition Procedure: Errorless training condition

Detailed Description:
Difficulty finding words is common in patients with aphasia subsequent to left hemisphere stroke. This study will compare two cognitive therapies for the treatment of acquired word finding difficulties. The therapies use different types of cues. All participants will receive both therapies. Participants in this study will undergo a comprehensive and detailed assessment of language and other cognitive skills. The two treatments will be compared for their efficacy.

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 78 participants
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Learning Paradigms in Aphasia Rehabilitation
Study Start Date : July 2004
Primary Completion Date : June 2009
Study Completion Date : June 2009

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Aphasia
U.S. FDA Resources

Arm Intervention/treatment
Experimental: Errorful training condition
A type of anomia rehabilitation paradigm which allows for errors. The intervention involves providing minimal auditory cues to allow for errors in picture naming.
Procedure: Errorful training condition
Errorful training condition: Participant saw a picture and named it without any cues. If an error was produced, the cue with the least amount of information was provided (e.g. for "pumpkin", "pu"). Cues with increasing information were provided until the picture was correctly named (e.g. for "pumpkin": "pump", "pumpki", then "pumpkin"). Once the correct name was provided, the trial ended.
Experimental: Errorless training condition
A type of anomia rehabilitation paradigm in which the situation surrounding the performance of the desired task (i.e., picture naming) is controlled to prevent errors. The intervention involves providing maximal auditory cues to prevent errors in picture naming.
Procedure: Errorless training condition
Errorless learning (EL) condition: Participant saw a picture with its name, and repeated the word. The participant continued to name the picture as the auditory cues provided less and less of the word (e.g. for "banana" she would hear "banan", "bana" then "ba" and finally no cue). If an error was produced at any stage, the whole word was presented, the participant repeated it, and the trial ended.



Primary Outcome Measures :
  1. Improved picture naming of trained words. [ Time Frame: Following conclusion of word treatment. ]
    Overall accuracy of named trained items


Secondary Outcome Measures :
  1. Improved picture naming of trained words. [ Time Frame: At 6 months after conclusion of word treatment ]
    Overall accuracy of named trained items

  2. Improved picture naming of untrained words. [ Time Frame: Following conclusion of word treatment. ]
    Overall accuracy of named untrained items

  3. Improved picture naming of untrained words. [ Time Frame: At 6 months after conclusion of word treatment ]
    Overall accuracy of named untrained items



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Word finding difficulty subsequent to stroke, traumatic brain injury, brain surgery or other brain damage occuring at least 6 month prior to participation
  • Ability to attend 2 sessions per week for several months at Georgetown University in Washington, DC

Exclusion Criteria:

  • History of learning disabilities
  • Best corrected vision less than 20/40
  • Corrected hearing within functional limits
  • Less than 10 years formal education
  • Significant memory or comprehension problems

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00494520


Locations
United States, District of Columbia
Georgetown University Medical Center
Washington, D.C., District of Columbia, United States, 20057
Sponsors and Collaborators
Georgetown University
Investigators
Principal Investigator: Rhonda B. Friedman, Ph.D. Georgetown University

Additional Information:
Responsible Party: Georgetown University
ClinicalTrials.gov Identifier: NCT00494520     History of Changes
Other Study ID Numbers: R01DC006934-01 ( U.S. NIH Grant/Contract )
First Posted: June 29, 2007    Key Record Dates
Last Update Posted: September 19, 2017
Last Verified: April 2014
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Keywords provided by Georgetown University:
Anomia
Aphasia
Traumatic Brain Injury
Cerebrovascular Accident

Additional relevant MeSH terms:
Brain Injuries
Brain Injuries, Traumatic
Aphasia
Stroke
Anomia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Craniocerebral Trauma
Trauma, Nervous System
Wounds and Injuries
Speech Disorders
Language Disorders
Communication Disorders
Neurobehavioral Manifestations
Neurologic Manifestations
Signs and Symptoms
Cerebrovascular Disorders
Vascular Diseases
Cardiovascular Diseases