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Cognitive Therapy to Improve Word Finding

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified November 2005 by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).
Recruitment status was:  Recruiting
Information provided by:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Identifier:
First received: June 28, 2007
Last updated: March 10, 2009
Last verified: November 2005
Adults who sustain brain damage due to stroke, traumatic injury or surgery may develop difficulty finding words. This study compares the effectiveness of two behavior-based programs to improve picture naming ability in these individuals.

Condition Intervention
Traumatic Brain Injury
Cerebrovascular Accident
Procedure: Cueing systems to improve picture naming

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Learning Paradigms in Aphasia Rehabilitation

Resource links provided by NLM:

Further study details as provided by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD):

Primary Outcome Measures:
  • Improved picture naming of trained words.

Secondary Outcome Measures:
  • Improved picture naming of untrained words.

Estimated Enrollment: 40
Study Start Date: July 2004
Estimated Study Completion Date: June 2009
Detailed Description:
Difficulty finding words is common in patients with aphasia subsequent to left hemisphere stroke. This study will compare two cognitive therapies for the treatment of acquired word finding difficulties. The therapies use different types of cues. All participants will receive both therapies. Participants in this study will undergo a comprehensive and detailed assessment of language and other cognitive skills. The two treatments will be compared for their efficacy.

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Word finding difficulty subsequent to stroke, traumatic brain injury, brain surgery or other brain damage occuring at least 6 month prior to participation
  • Ability to attend 2 sessions per week for several months at Georgetown University in Washington, DC

Exclusion Criteria:

  • History of learning disabilities
  • Best corrected vision less than 20/40
  • Corrected hearing within functional limits
  • Less than 10 years formal education
  • Significant memory or comprehension problems
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00494520

United States, District of Columbia
Georgetown University Medical Center
Washington, District of Columbia, United States, 20057
Sponsors and Collaborators
National Institute on Deafness and Other Communication Disorders (NIDCD)
Principal Investigator: Rhonda B. Friedman, Ph.D. Georgetown University
  More Information

Additional Information: Identifier: NCT00494520     History of Changes
Other Study ID Numbers: R01DC006934-01 
Study First Received: June 28, 2007
Last Updated: March 10, 2009

Keywords provided by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD):
Traumatic Brain Injury
Cerebrovascular Accident

Additional relevant MeSH terms:
Brain Injuries
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Craniocerebral Trauma
Trauma, Nervous System
Wounds and Injuries
Cerebrovascular Disorders
Vascular Diseases
Cardiovascular Diseases
Speech Disorders
Language Disorders
Communication Disorders
Neurobehavioral Manifestations
Neurologic Manifestations
Signs and Symptoms processed this record on February 20, 2017