Photosensitivity of the Skin Under Azathioprin in Renal Transplant Recipients

This study has been completed.
Information provided by (Responsible Party):
University of Zurich Identifier:
First received: June 19, 2007
Last updated: January 28, 2013
Last verified: January 2013
Photosensitivity of the skin to UVA and UVB will be determined

Condition Intervention Phase
Skin Cancer
Drug: Discontinuation of Azathioprin
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Diagnostic
Official Title: Photosensitivity of the Skin Under Azathioprin in Renal Transplant Recipients

Further study details as provided by University of Zurich:

Primary Outcome Measures:
  • Photosensitivity of the skin to UVA and UVB [ Time Frame: 2 years ] [ Designated as safety issue: No ]

Enrollment: 25
Study Start Date: June 2007
Study Completion Date: March 2011
Primary Completion Date: December 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
one arm only. Crossover study
Drug: Discontinuation of Azathioprin
Discontinuation of Azathioprin

Detailed Description:

Photosensitivity of the skin to UVA and UVB in renal transplant recipients with and without azathioprine will be determined. Azathioprine will be discontinued and photosensitivity determined after a wash-out period of three months

  • Trial with medicinal product

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Inclusion criteria:

  • Renal transplant recipients under azathioprin

Exclusion criteria:

  • Treatment with Prograf (Tacrolimus)
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Please refer to this study by its identifier: NCT00492895

Clinic for Dermatology, University Hospital of Zurich
Zurich, Switzerland
Sponsors and Collaborators
University of Zurich
Principal Investigator: Günther Hofbauer, M.D UniversitaetsSpital Zuerich
  More Information

Responsible Party: University of Zurich Identifier: NCT00492895     History of Changes
Other Study ID Numbers: 2007DR2040 
Study First Received: June 19, 2007
Last Updated: January 28, 2013
Health Authority: Switzerland: Swissmedic processed this record on May 30, 2016