This site became the new on June 19th. Learn more.
Show more Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu
Give us feedback

Duodenal Jejunal Bypass for Type 2 Diabetes (DJBD) (DJBD)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified July 2007 by Ferzli, George S., M.D. F.A.C.S..
Recruitment status was:  Recruiting
Information provided by:
Ferzli, George S., M.D. F.A.C.S. Identifier:
First received: June 11, 2007
Last updated: July 10, 2007
Last verified: July 2007
Study the effect of Duodenal jejunal bypass on human adults with type 2 diabetes.

Condition Intervention Phase
Diabetes Mellitus Procedure: duodenal jejunal bypass Phase 1

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Clinical Evaluation of the Effect of Duodenal Jejunal Bypass on Type Two Diabetes in Non Obese Adults

Further study details as provided by Ferzli, George S., M.D. F.A.C.S.:

Primary Outcome Measures:
  • control of type 2 diabetes in non obese adults [ Time Frame: two years ]

Secondary Outcome Measures:
  • CCK FFA,Cholesterol,Ghrelin,C-peptide,HbA1c,Gastrin,GIP,Triglycerides,Insulin [ Time Frame: 2 years ]

Estimated Enrollment: 50
Study Start Date: June 2007
Detailed Description:
Adults non obese ( BMI less than 34 ) will undergo duodenal jejunal bypass. The Outcome measures: Blood Sugar, Insulin,HbA1c, CCK,Gastrin, GIP1and 2, Ghrelin, Cholesterol, Triglycerides,FFA, C-Peptide.

Ages Eligible for Study:   20 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Adults age 20-65
  • Clinical diagnosis of type 2 diabetes
  • Non obese with BMI less than 34.
  • Oral agents or insulin to control T2DM.
  • Inadequate control of diabetes as defined as HbA1c>/7.5
  • Understanding of the mechanisms of action of the treatment

Exclusion Criteria:

  • Children with type 1 diabetes
  • Obese with BMI over 34
  • Coagulopathy
  • Liver cirrhosis
  • Unable to comply with study requirements, follow-up or give valid consent
  • Currently pregnant
  • Previous upper abdominal surgery
  • Inabilty to tolerate general anesthesia
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00487526

Contact: George S Ferzli, MD, F.A.C.S 718-667-8100

Dominican Republic
Center for Advance Medicine Abel Gonzalez Recruiting
Santo Domingo, Dominican Republic
Contact: Abel Gonzalez, MD    809 543 79 81   
Contact    809 227 22 35      
Sponsors and Collaborators
Ferzli, George S., M.D. F.A.C.S.
Principal Investigator: George S Ferzli, MD F.A.C.S SUNY Downstate
  More Information Identifier: NCT00487526     History of Changes
Other Study ID Numbers: AS07006
Study First Received: June 11, 2007
Last Updated: July 10, 2007

Keywords provided by Ferzli, George S., M.D. F.A.C.S.:
Duodenal jejunal
type 2 diabetes
non-obese adults

Additional relevant MeSH terms:
Diabetes Mellitus
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases processed this record on September 21, 2017