Cardiovascular Risk Factors in an Ambulatory Urban Patient Population (AsuRiesgo)
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|ClinicalTrials.gov Identifier: NCT00486993|
Recruitment Status : Completed
First Posted : June 15, 2007
Last Update Posted : November 8, 2016
According to WHO estimations, cardiovascular diseases (CVDs) are the number one cause of death globally. More people die annually from CVDs than from any other cause. An estimated 17.5 million people died from CVDs in 2005, representing 30% of all global deaths. Of these deaths, an estimated 7.6 million were due to coronary heart disease and 5.7 million were due to stroke.
Over 80% of CVD deaths take place in low- and middle-income countries and occur almost equally in men and women. In Paraguay, prevalence of classic risk factors, as well as new ones, like the metabolic syndrome are not completely known.
Government health policies in industrialized countries are focusing on programs to modify cardiovascular risk factors. In developing countries, prevention of coronary heart disease and stroke through modification of cardiovascular risk factors are not playing a large role at the moment.
The aim of this study is to define the effects of changes in lifestyle on cardiovascular risk factors, when added to optimized standard pharmacological therapy for arterial hypertension, diabetes mellitus and hyperlipidemia, in an ambulatory urban patient population.
|Condition or disease||Intervention/treatment|
|Cardiovascular Risk Factors Metabolic Syndrome Lifestyle Modification Coronary Artery Disease Stroke||Behavioral: Dietary and nutritional modification Behavioral: Stop smoking Behavioral: Regular physical activities Behavioral: Weight reduction to normal ranges Behavioral: Regular intake of polyphenols, esp. from Ilex paraguayensis|
|Study Type :||Observational|
|Actual Enrollment :||18287 participants|
|Official Title:||Estimation of Prevalence and Assessment of the Effects of Modification of Cardiovascular Risk Factors in an Ambulatory Urban Patient Population|
|Study Start Date :||May 2006|
|Actual Primary Completion Date :||July 2014|
|Actual Study Completion Date :||July 2014|
unselected outpatient population
|Behavioral: Dietary and nutritional modification Behavioral: Stop smoking Behavioral: Regular physical activities Behavioral: Weight reduction to normal ranges Behavioral: Regular intake of polyphenols, esp. from Ilex paraguayensis|
- cardiovascular mortality [ Time Frame: one year ]
- mortality, other causes [ Time Frame: one year ]
- acute myocardial infarction [ Time Frame: one year ]
- stroke [ Time Frame: one year ]
- acute coronary syndrome [ Time Frame: one year ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00486993
|Hospital Central Instituto de Prevision Social|
|Asuncion, Dep. Central, Paraguay, 1749|
|Principal Investigator:||Derliz Mereles, MD||Heidelberg University|