Cardiovascular Risk Factors in an Ambulatory Urban Patient Population (AsuRiesgo)
Recruitment status was Active, not recruiting
According to WHO estimations, cardiovascular diseases (CVDs) are the number one cause of death globally. More people die annually from CVDs than from any other cause. An estimated 17.5 million people died from CVDs in 2005, representing 30% of all global deaths. Of these deaths, an estimated 7.6 million were due to coronary heart disease and 5.7 million were due to stroke.
Over 80% of CVD deaths take place in low- and middle-income countries and occur almost equally in men and women. In Paraguay, prevalence of classic risk factors, as well as new ones, like the metabolic syndrome are not completely known.
Government health policies in industrialized countries are focusing on programs to modify cardiovascular risk factors. In developing countries, prevention of coronary heart disease and stroke through modification of cardiovascular risk factors are not playing a large role at the moment.
The aim of this study is to define the effects of changes in lifestyle on cardiovascular risk factors, when added to optimized standard pharmacological therapy for arterial hypertension, diabetes mellitus and hyperlipidemia, in an ambulatory urban patient population.
Cardiovascular Risk Factors
Coronary Artery Disease
Behavioral: Dietary and nutritional modification
Behavioral: Stop smoking
Behavioral: Regular physical activities
Behavioral: Weight reduction to normal ranges
Behavioral: Regular intake of polyphenols, esp. from Ilex paraguayensis
|Study Design:||Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Prevention
|Official Title:||Estimation of Prevalence and Assessment of the Effects of Modification of Cardiovascular Risk Factors in an Ambulatory Urban Patient Population|
- cardiovascular mortality [ Time Frame: one year ]
- mortality, other causes [ Time Frame: one year ]
- acute myocardial infarction [ Time Frame: one year ]
- stroke [ Time Frame: one year ]
- acute coronary syndrome [ Time Frame: one year ]
|Study Start Date:||May 2006|
|Estimated Study Completion Date:||May 2016|
|Estimated Primary Completion Date:||May 2014 (Final data collection date for primary outcome measure)|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00486993
|Hospital Central Instituto de Prevision Social|
|Asuncion, Dep. Central, Paraguay, 1749|
|Principal Investigator:||Derliz Mereles, MD||Heidelberg University|